876921-16-3Relevant academic research and scientific papers
8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors-Part II
Bromidge, Steven M.,Bertani, Barbara,Borriello, Manuela,Bozzoli, Andrea,Faedo, Stefania,Gianotti, Massimo,Gordon, Laurie J.,Hill, Matthew,Zucchelli, Valeria,Watson, Jeannette M.,Zonzini, Laura
, p. 2338 - 2342 (2009)
8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones have been identified as highly potent 5-HT1A/B/D receptor antagonists with and without additional SerT activity and a high degree of selectivity over hERG potassium channels. Modula
FUSED TRICYCLIC DERIVATIVES FOR THE TREATMENT OF PSYCHOTIC DISORDERS
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Page/Page column 41, (2010/10/20)
Compounds of formula (I) wherein R1, R2, X, A, Y, B, Z1, Q, p, r and s are defined in the specification for treating inter alia psychotic disorders, depressive disorders, anxiety disorders and sexual dysfunctions.
