Bioorganic and Medicinal Chemistry Letters p. 2338 - 2342 (2009)
Update date:2022-08-05
Topics:
Bromidge, Steven M.
Bertani, Barbara
Borriello, Manuela
Bozzoli, Andrea
Faedo, Stefania
Gianotti, Massimo
Gordon, Laurie J.
Hill, Matthew
Zucchelli, Valeria
Watson, Jeannette M.
Zonzini, Laura
8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones have been identified as highly potent 5-HT1A/B/D receptor antagonists with and without additional SerT activity and a high degree of selectivity over hERG potassium channels. Modula
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