877-96-3

Basic information

• Product Name: 1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE
• Synonyms: N,N-DIMETHYL-3-PIPERAZINOPROPYLAMINE;N,N-DIMETHYL-1-PIPERAZINEPROPANAMINE;RARECHEM AH CK 0090;1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE;1-(3-dimethylpropyl)piperazine;1-(3-Dimethylaminopropyl)piperazine 97%;1-Piperazinepropanamine,N,N-dimethyl-(9CI);N,N-Dimethyl-1-piperazinepropanamine, N,N-Dimethyl-3-piperazinopropylamine
• CAS NO: 877-96-3
• Molecular Formula: C₉H₂₁N₃
• Molecular Weight: 171.28
• Product Categories: PIPERIDINE;Building Blocks;C9;Chemical Synthesis;Heterocyclic Building Blocks;Piperazines
• Mol File: 877-96-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 77 °C
• Flash Point: 94 °C
• Appearance: /
• Density: 0.911 g/cm³
• Vapor Pressure: 0.0447mmHg at 25°C
• Refractive Index: n20/D 1.478
• PKA: 9.67±0.28(Predicted)
• Sensitive: Air Sensitive
• BRN: 506940
• CAS DataBase Reference: 1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE(877-96-3)
• EPA Substance Registry System: 1-[3-(DIMETHYLAMINO)PROPYL]PIPERAZINE(877-96-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• F: 10-34
• HazardClass: 8
• Hazardous Substances Data: 877-96-3(Hazardous Substances Data)

Usage

Chemical Properties

Clear light yellow liquid

InChI:InChI=1/C9H21N3/c1-11(2)6-3-7-12-8-4-10-5-9-12/h10H,3-9H2,1-2H3

Upstream product

• 77279-01-7 C₁₄H₂₇N₃O₃ 
• 656803-51-9 4-(2-methoxycarbonylethyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 110-85-0 piperazine 
• 5407-04-5 3-(dimethylamino)propyl chloride hydrochloride 

Downstream Products

• 878161-38-7 N-[bis(4-methylphenyl)methyl]-4-(3-dimethylaminopropyl)piperazine-1-carboxamide 
• 1369390-22-6 [3-(4-(4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl)-piperazin-1-yl)-propyl]-trimethyl-ammonium trifluoroacetate salt 

Relevant articles and documents

Design and synthesis of novel sulfonamide-containing bradykinin hB 2 receptor antagonists. Synthesis and structure-relationships of α,α-tetrahydropyranylglycine

A series of α,α-cycloalkylglycine sulfonamide compounds of general formula 1 has previously been identified by our group as selective human B2(hB2) receptor antagonists. Here we report the in vitro and in vivo BK antagonist activity

Anti-leishmanial lepidine derivatives

The subject 8-[6-(N-heterocyclic-substituted)hexylamino]-6-methoxy lepidineerivatives have the formula: STR1 wherein Z represents methyl or, together with the two contiguous carbon atoms, the benzo moiety of a benzopiperazinyl derivative when Y is --N(R')--, n is an integer from 0 to 2; Y represents --O--, --S--, --S(O)--, --S(O)2 --, and --N(R')--; R' represents hydrogen, alkyl, lower alkyl, R" substituted lower alkyl, cycloalkyl, aryl, sulfonyl, saturated 1,4-diazepinyl, lower alkyl N-cyanocarboximidothioate, or --C(O)R'"; R" represents at least one of hydroxy, alkoxy, aralkoxy, amino, lower alkyl substituted amino, phenyl, halogenated phenyl, or sufonyl; and R'" represents lower alkyl, alkoxy, aralkoxy, amino, lower alkyl substituted amino or aryl substituted amino; and pharmaceutically acceptable salts thereof. These derivatives afford improvement in means for the chemotherapy of leishmaniasis when administered parenterally or orally to infected animals.