877149-08-1

Usage

Uses

Used in Pharmaceutical Research:
4-bromo-2-methoxy-6-methylbenzoic acid is used as a building block for the preparation of biologically active molecules, contributing to the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
4-bromo-2-methoxy-6-methylbenzoic acid serves as an intermediate in the synthesis of various organic compounds, facilitating the creation of new chemical entities with diverse properties and functions.
Used in Drug Development:
4-bromo-2-methoxy-6-methylbenzoic acid is utilized in the design and synthesis of new pharmaceutical agents, enhancing the discovery of novel therapeutics for the treatment of various diseases and conditions.
Used in Agrochemicals:
In the agrochemical industry, 4-bromo-2-methoxy-6-methylbenzoic acid is employed as a precursor or building block for the development of new agrochemicals, such as pesticides and herbicides, to improve crop protection and yield.
Used in Material Science:
4-bromo-2-methoxy-6-methylbenzoic acid is applied in the field of material science for the synthesis of new materials with specific properties, such as conductivity, magnetism, or optical characteristics, for various technological applications.

Upstream product

• 877149-12-7 4-bromo-2-methoxy-6-methylbenzamide 
• 1181458-21-8 (4-Bromo-2-methoxy-6-methyl-phenyl)-amine hydrobromide 
• 50868-73-0 2-methoxy-6-methylbenzeneamine 
• 877149-05-8 4-bromo-2-methoxy-6-methyl-benzonitrile 
• 348169-39-1 4-bromo-2-methoxy-6-methyl-phenylamine 
• 1244949-43-6 4-bromo-2-methoxy-6-methyl-benzaldehyde 

Downstream Products

• 1335556-16-5 phenyl 4-(benzyloxy)-2-isopropyl-6-methyl-7-(trifluoromethyl)isoindoline-5-carboxylate 
• 1254348-93-0 phenyl 4-ethenyl-2-methoxy-6-methylbenzoate 
• 1254346-10-5 phenyl 4-formyl-2-methoxy-6-methylbenzoate 
• 1254348-94-1 C₁₆H₁₃BrO₄ 
• 1254346-14-9 phenyl 2-(benzyloxy)-3-bromo-4-formyl-6-methylbenzoate 
• 1254348-95-2 C₁₅H₁₁BrO₄ 
• 1254348-96-3 C₂₃H₁₇F₃O₄ 
• 1335557-40-8 C₂₃H₁₉F₃O₄ 
• 1335557-41-9 C₂₃H₁₈BrF₃O₄ 
• 1335557-42-0 C₂₄H₂₁F₃O₅ 
• 1335557-43-1 C₂₄H₁₉Cl₂F₃O₃ 
• 1335556-22-3 phenyl 4-(benzyloxy)-7-methoxy-6-methyl-2-tert-pentylisoindoline-5-carboxylate 
• 1254347-06-2 phenyl 4-bromo-2-hydroxy-6-methylbenzoate 
• 1254347-07-3 phenyl 4-bromo-6-hydroxy-3-methoxy-2-methylbenzoate 

Relevant academic research and scientific papers

Tetracycline compounds

The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula I and its therapeutic use.

SUBSTITUTED 4-AMINOBENZAMIDES AS KCNQ2/3 MODULATORS

The invention relates to substituted 4-aminobenzamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Synthesis and biological evaluation of 8-aminomethyltetracycline derivatives as novel antibacterial agents

The C-8 position of the tetracyclines has been largely underexplored because of limitations in traditional semisynthetic techniques. Employing a total synthetic approach allowed for modifications at the C-7 and C-8 positions, enabling the generation of structure-activity relationships for overcoming the two most common tetracycline bacterial-resistance mechanisms: ribosomal protection (tet(M)) and efflux (tet(A)). Ultimately, several compounds were identified with balanced activity against both Gram-positive and Gram-negative bacteria, including pathogens bearing both types of tetracycline-resistance mechanisms. Compounds were screened in a murine systemic infection model to rapidly identify compounds with oral bioavailability, leading to the discovery of several compounds that exhibited efficacy when administered orally in murine pyelonephritis and pneumonia models.

SUBSTITUTED 4-AMINOBENZAMIDES AS KCNQ2/3 MODULATORS

Substituted 4-aminobenzamides, pharmaceutical compositions containing these compounds and also methods of using these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

TETRACYCLINE ANALOGS

The present invention is directed to a compound represented by Structural Formula (I), or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.

POLYCYCLIC TETRACYCLINE COMPOUNDS

The present invention is directed to a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.

ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS

The present invention is directed to compounds of formula (I), wherein R1 is a ring and n is a number from 1 to 8. The invention also relates to use of the compounds in therapy as metabotropic glutamate receptor modulators, particularly in neurological and psychiatric disorders.