87733-69-5

Upstream product

• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 124-40-3 dimethyl amine 
• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 

Downstream Products

• 146467-16-5 ((S)-5-Diazo-1-dimethylcarbamoyl-4-oxo-pentyl)-carbamic acid benzyl ester 
• 146467-18-7 (S)-2-Dimethylcarbamoyl-5-oxo-piperidine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of 5-oxo-L-pipecolic acid derivatives by rhodium(II) acetate catalyzed cyclization of diazoketones

A convenient synthesis of 5-oxo-L-pipecolic acid derivatives is described. The key step involves the rhodium(II) acetate catalysed N-H insertion reaction of diazoketones, which are derived from L-glutamic acid.

Regioselective amidation of aspartic and glutamic acid

The synthesis of N-protected aspartic 1-amide and glutamic 1-amide from aspartic and glutamic acids via regioselective amidation of intermediate 5-oxazolidinone derivatives with aqueous ammonia or amine is described.