877399-73-0

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester
• Synonyms: 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester;tert-butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate;1-(4-BOC-piperazino)-4-iodopyrazole;1-(4-BOC-piperidyl)-4-iodopyrazole;1-Boc-4-(4-iodo-1H-pyrazol-1-yl)piperidine;4-(4-Iodo-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester;tert-Butyl 4-(4-iodopyrazolyl)piperidinecarboxylate;1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-
• CAS NO: 877399-73-0
• Molecular Formula: C₁₃H₂₀IN₃O₂
• Molecular Weight: 377.22
• Mol File: 877399-73-0.mol
• Article Data: 30

Chemical Properties

• Melting Point: 97 °C
• Boiling Point: 430.596°C at 760 mmHg
• Flash Point: 214.217°C
• Appearance: /Solid
• Density: 1.603g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.08±0.19(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester(877399-73-0)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester(877399-73-0)

Safety Data

• Hazardous Substances Data: 877399-73-0(Hazardous Substances Data)

Usage

General Description

1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester, also known as Tert-butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate, is a chemical compound used in organic synthesis and pharmaceutical research. It is commonly employed as a building block in the development of new drugs and agrochemicals. This ester derivative is known for its potential therapeutic activities and is used as a starting material in the production of various pharmaceuticals and biologically active compounds. Its unique chemical structure and properties make it a valuable component in drug discovery and development efforts.

InChI:InChI=1/C13H20IN3O2/c1-13(2,3)19-12(18)16-6-4-11(5-7-16)17-9-10(14)8-15-17/h8-9,11H,4-7H2,1-3H3

Upstream product

• 3469-69-0 4-iodopyrazole 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 189205-49-0 4-methanesulfonylpiperidine-1-carboxylic acid tert-butyl ester 
• 118811-07-7 tert-butyl 4-(tosyloxy)piperidin-1-carboxylate 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 24608-52-4 tert-butyl chloroformate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1229457-94-6 4-(4-iodo-1H-pyrazol-1-yl)piperidine 

Downstream Products

• 877399-74-1 tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate 
• 1190875-39-8 (1-{1-[(tert-butoxy)carbonyl]piperidin-4-yl}-1H-pyrazol-4-yl)boronic acid 
• 1613332-92-5 3-((2,5-difluorophenyl)ethynyl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 
• 1613333-44-0 4-(4-(3-((2,5-difluorophenyl)ethynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl)piperidine1-carboxylic acid tert-butyl ester 
• 1613332-90-3 3-((2,5-dichlorophenyl)ethynyl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 
• 1613333-43-9 4-(4-(3-((2,5-dichlorophenyl)ethynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl)piperidine1-carboxylic acid tert-butyl ester 
• 1613333-41-7 4-(4-(1-(phenylsulfonyl)-3-((trimethylsilyl)ethynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 1613333-40-6 4-(4-(3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl)piperidine1-carboxylic acid tert-butyl ester 
• 1613332-89-0 3-((2-chlorophenyl)ethynyl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2.3-b]pyridine 
• 1613333-39-3 4-(4-(3-((2-chlorophenyl)ethynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 1428476-86-1 4-(4-{6-amino-5-[(R)-1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-3-yl}-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 877399-52-5 crizotinib 

Relevant articles and documents

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