87753-10-4

Upstream product

• 14401-51-5 4-chlorobenzamidine hydrochloride 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 19563-04-3 p-chlorobenzamidine 

Downstream Products

• 268557-84-2 2-(4-chlorophenyl)-4-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as sigma-1 (σ1) receptor antagonists for the treatment of pain

The synthesis and biological evaluation of new series of 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as selective sigma-1 receptor (σ1R) antagonists are reported. The receptor affinities of new compounds

Pyrimidine derivatives useful in the treatment of insulin resistance and hyperglycemia

This invention provides compounds of Formula I having the structure: wherein: B is alkyl of 1-4 carbons or alkoxy of 1-4 carbons; R1 is aryl or Het optionally substituted with R6; R2 and R3 are each independentl

Substituted 4-amino-2-aryl-cyclopenta[d]pyrimidines, their production and use and pharmaceutical preparations containing same

The present invention relates to compounds of formula (I) wherein R1, R2and R3have the meanings given in the claims. Said compounds are valuable active agents in medicaments for the treatment and prophylaxis of diseases, f