87753-17-1

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 22945-27-3 cyclohexanone-2-carboxamide 
• 104-88-1 4-chlorobenzaldehyde 
• 908009-71-2 3-(p-chlorophenyl)-2,4-diazabicylo[4.2.0]-1⁽⁶⁾,2-dien-5-one 
• 908009-85-8 2-(p-chlorophenyl)-7,8-dihydro-3H-quinazolin-4-one 
• 62582-89-2 2-(4-Chlorophenyl)-1,2,5,6,7,8-hexahydroquinazolin-4(3H)-one 
• 14401-51-5 4-chlorobenzamidine hydrochloride 
• 908009-78-9 2-(p-chlorophenyl)-6-(phenylsulfonyl)-5,6,7,8-tetrahydro-3H-quinazolin-4-one 

Relevant academic research and scientific papers

TETRAHYDRO- AND DIHYDROQUINAZOLINONES

The present invention relates to the use of tetrahydro- and dihydroquinazolinones of formula (I) as protein kinase activators or inhibitors, a method for their manufacture, their use for the preparation of a medicament for the treatment of diseases, their

Access to variously substituted 5,6,7,8-tetrahydro-3H-quinazolin-4-ones via Diels-Alder adducts of phenyl vinyl sulfone to cyclobutene-annelated pyrimidinones

Under basic conditions (Et3N, dioxane), the aromatic amidines 4 and also S-methylisothiourea 4g cleanly undergo Michael addition to methyl 2-chloro-2-cyclopropylideneacetate (5), followed by intramolecular nucleophilic substitution, cyclopropyl

A Novel Ring Transformation of Oxazinones and Azetidinones into Pyrimidinones

Azetidinones or oxazinones, being easily prepared from enamines and acyl isocyanates, were transformed into highly substituted 4(3H)-pyrimidinones upon treatment with ammonium acetate.This novel ring transformation was also accomplished through a one-pot

A Novel Preparation of 5,6,7,8-Tetrahydroquinazolin-4(3H)-ones

Cyclocondensation of 2-oxocyclohexanecarboxamide with aldehydes and ammonia affords 4-oxo-1,2,5,6,7,8-hexahydroquinazolines which are conveniently dehydrogenated to the title compounds by treatment with palladium-on-carbon catalyst in boiling toluene.