877662-84-5Relevant articles and documents
Towards the rubromycins: An efficient synthesis of a suitable isocoumarin precursor, its lactam analogue, and palladium-catalyzed couplings
Brasholz, Malte,Luan, Xiaosong,Reissig, Hans-Ulrich
, p. 3571 - 3580 (2005)
6-Iodoisocoumarin 4 and its aza-analogue, 6-iodo-1-oxo-isoquinoline 29, were efficiently prepared from vanillin in seven and six steps, respectively. Key transformations in their syntheses were achieved by directed ortho-lithiation and variations of Horne