877681-12-4

Basic information

• Product Name: 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE
• Synonyms: 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE;5-(Trifluoromethoxy)-1H-benzo[d]imidazol-2(3H)-one;5-(Trifluoromethoxy)benzoimidazol-2(3H)-one
• CAS NO: 877681-12-4
• Molecular Formula: C8H5F3N2O2
• Molecular Weight: 218.13
• Mol File: 877681-12-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE(877681-12-4)
• EPA Substance Registry System: 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE(877681-12-4)

Safety Data

• Hazardous Substances Data: 877681-12-4(Hazardous Substances Data)

Usage

General Description

5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE is a chemical compound with the molecular formula C8H7F3N2O2. It is a benzimidazole derivative with a trifluoromethoxy group attached to the benzene ring. 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE has potential applications in pharmaceuticals and agrochemicals due to its unique structure and properties. It may be used as a building block in the synthesis of new drugs or as an intermediate in the production of agrochemicals. Further research and testing are needed to fully understand and utilize the potential uses of 5-TRIFLUOROMETHOXY-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE.

Upstream product

• 658-89-9 4-(trifluoromethoxy)benzene-1,2-diamine 
• 57-13-6 urea 
• 2267-23-4 2-nitro-4-trifluoromethoxyaniline 
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• 530-62-1 1,1'-carbonyldiimidazole 
• 1737-06-0 N-(4-(trifluoromethoxy)phenyl)acetamide 
• 461-82-5 4-(trifluoromethoxy)aniline 
• 1351534-05-8 2-amino-4-trifluoromethoxy-N-acetylaniline 

Downstream Products

• 886465-16-3 2-chloro-6-(trifluoromethoxy)-1H-benzo[d]imidazole 
• 1351534-24-1 (2R)-2-[2-chloro-5-[[3-(6-methoxybenzisoxazol-3-yl)-2-oxo-5-trifluoromethoxybenzimidazol-1-yl]methyl]phenoxy]propanoic acid 
• 1073559-38-2 3-phenyl-8-{5-[(trifluoromethyl)oxy]-1H-benzimidazol-2-yl}-1-oxa-3,8-diazaspiro-[4.5]decan-2-one 
• 1073558-81-2 3-phenyl-8-{5-[(trifluoromethyl)oxy]-1H-benzimidazol-2-yl}-1-oxa-3,8-diazaspiro-[4.5]decan-2-one hydrochloride 

Relevant articles and documents

CYANOPYRROLIDINE DERIVATIVES WITH ACTIVITY AS INHIBITORS OF USP30

The present invention relates to a class of substituted-cyanopyrrolidines of Formula (I) with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having utility i

BENZIMIDAZOLES WITH A HETERO SPIRO-DECANE RESIDUE AS NPY-Y5 ANTAGONISTS

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salts, solvates, stereoisomers thereof, formula (I), R1 may be C1-C4 alkyl, aryl or heteroaryl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; R2 may be halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano, nitro; or aryl, heteroaryl or heterocycle, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; or R2 may correspond to -0-R3; R3 is a 6-membered aromatic carbocyclic ring which may contain 1 or 2 nitrogen X is carbon or oxygen; Z is carbon or nitrogen; G is a fused 6-membered aromatic carbocyclic ring which may contain 1 or 2 nitrogen; m may be 0 or an integer ranging from 1 to 4; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as NPY- Y5 receptor antagonists.