87769-57-1Relevant academic research and scientific papers
A regioselective one-pot, three component synthesis of 6-Aryl-4-cyano-3(2H) -pyridazinones in water
Rimaz, Mehdi,Khalafy, Jabbar,Moghadam, Peyman Najafi
, p. 1396 - 1401 (2011/04/16)
A series of 4-cyano-3(2H)-pyridazinones bearing different aryl substituents in the 6-position of the pyridazinone ring was synthesized regioselectively using a novel efficient one-pot three component reaction of alkyl 2-cyanoacetates with arylglyoxals in the presence of hydrazine hydrate at room temperature in water. CSIRO 2010.
Polyfunction al nitriles in organic syntheses: A novel route to aminopyrroles, pyridazines and pyrazolo[3,4-c]pyridazines
Al-Mousawi, Saleh M.,Moustafa, Sherief,Meier, Herbert,Kolshorn, Heinz,Elnagdi, Mohamed Hilmy
experimental part, p. 798 - 806 (2009/05/27)
Phenacylmalononitrile 1 reacts with dimethylformamide dimethyl acetal to yield an enaminone which could be readily converted into a pyrrole or an aminopyridazine by treating with ammonium acetate and hydrazine hydrate, respectively. Compound 1 reacted wit
