87797-64-6Relevant articles and documents
Synthesis of 2,4-Diarylquinoline Derivatives via Chloranil-Promoted Oxidative Annulation and One-Pot Reaction
Cheng, Dongping,Pu, Yueqi,Shen, Jing,Xu, Xiaoliang,Yan, Jizhong,Yan, Xianhang
, p. 1833 - 1840 (2020)
An oxidative annulation for the synthesis of 2,4-diarylquinolines from o -allylanilines is disclosed that uses recyclable reagent Chloranil as the oxidant. The corresponding products are obtained in moderate to excellent yields. Furthermore, a one-pot access to 2,4-di aryl quinolines from easily available anilines and 1,3-diarylpropenes is described as a highly atom-efficient protocol that involves oxidative coupling, rearrangement, and oxidative annulation.
Synthesis method of 2, 4-diarylquinoline compound
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Paragraph 0056-0065; 0090-0092, (2020/06/20)
The invention relates to a synthesis method of a 2, 4-diarylquinoline compound (II), which comprises the following steps: mixing a compound represented by a formula (I), an oxidizing agent and an organic solvent, heating to 60-80 DEG C, reacting for 1-2 hours, and carrying out after-treatment on the reaction solution to obtain a product (II). According to the synthesis method, a metal and other additives are not needed, operation is easy, raw materials are easy to obtain, and conditions are mild.
Synthesis of polysubstituted quinolines via transition-metal-free oxidative cycloisomerization of o -cinnamylanilines
Rehan, Mohammad,Hazra, Gurupada,Ghorai, Prasanta
, p. 1668 - 1671 (2015/04/14)
An efficient synthesis of 2-aryl 4-substituted quinolines from stable and readily available o-cinnamylanilines, prepared from anilines and cinnamylalcohols, has been developed. The reaction occurred via a regioselective 6-endo-trig intramolecular oxidative cyclization using KOtBu as a mediator and DMSO as an oxidant at rt. The reaction showed a broad substrate scope with good to excellent yields.