878197-92-3

Usage

Uses

Used in Pharmaceutical Industry:
(5-FLUOROIMIDAZO[1,2-A]PYRIDIN-2-YL)METHANOL is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It plays a crucial role in the development of new drugs and agrochemicals with improved efficacy and safety.
Used in Research and Development:
(5-FLUOROIMIDAZO[1,2-A]PYRIDIN-2-YL)METHANOL is utilized in research and development for the study of imidazole-containing compounds and their potential therapeutic applications. This helps in the discovery of new drugs and agrochemicals with novel mechanisms of action and improved pharmacological properties.

Upstream product

• 878197-67-2 5-fluoroimidazo[1,2-a]pyridine-2-carbaldehyde 

Downstream Products

• 878197-93-4 [5-(4-methyl-1-piperazinyl)imidazo[1,2-a]pyridine-2-yl]methanol 

Relevant academic research and scientific papers

Kilogram-scale synthesis of the CXCR4 antagonist GSK812397

An improved, scalable synthesis of the CXCR4 antagonist GSK812397 is described. This new route was recently scaled up in 50 L fixed equipment to afford 1.2 kg of drug substance in five steps with an overall yield of 20% and >99% chemical and enantiomeric

CHEMICAL COMPOUNDS

The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a

CHEMICAL COMPOUNDS

The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a

CHEMICAL COMPOUNDS

There is provided novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as C

CHEMCIAL COMPOUNDS

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.

CHEMICAL COMPOUNDS

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a recep