878197-92-3 Usage
Description
(5-FLUOROIMIDAZO[1,2-A]PYRIDIN-2-YL)METHANOL is a chemical compound that belongs to the class of imidazole derivatives. It is a white solid with the molecular formula C8H7FN2O and a molecular weight of 160.15 g/mol. Its chemical structure includes a fluorine-substituted imidazo[1,2-a]pyridine ring system, making it a valuable building block for the creation of novel bioactive molecules with potential pharmacological properties.
Uses
Used in Pharmaceutical Industry:
(5-FLUOROIMIDAZO[1,2-A]PYRIDIN-2-YL)METHANOL is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It plays a crucial role in the development of new drugs and agrochemicals with improved efficacy and safety.
Used in Research and Development:
(5-FLUOROIMIDAZO[1,2-A]PYRIDIN-2-YL)METHANOL is utilized in research and development for the study of imidazole-containing compounds and their potential therapeutic applications. This helps in the discovery of new drugs and agrochemicals with novel mechanisms of action and improved pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 878197-92-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,1,9 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 878197-92:
(8*8)+(7*7)+(6*8)+(5*1)+(4*9)+(3*7)+(2*9)+(1*2)=243
243 % 10 = 3
So 878197-92-3 is a valid CAS Registry Number.
878197-92-3Relevant articles and documents
Kilogram-scale synthesis of the CXCR4 antagonist GSK812397
Boggs, Sharon,Elitzin, Vassil I.,Gudmundsson, Kristjan,Martin, Michael T.,Sharp, Matthew J.
scheme or table, p. 781 - 785 (2010/04/22)
An improved, scalable synthesis of the CXCR4 antagonist GSK812397 is described. This new route was recently scaled up in 50 L fixed equipment to afford 1.2 kg of drug substance in five steps with an overall yield of 20% and >99% chemical and enantiomeric
CHEMICAL COMPOUNDS
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Page/Page column 45; 60, (2010/11/28)
The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a
CHEMCIAL COMPOUNDS
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Page/Page column 61, (2010/10/20)
The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
