87826-99-1Relevant academic research and scientific papers
Effect of a Lithocholic Acid Derivative on the Molecular Packing and Stability of Phospholipid Vesicles
Li, Zi-Chen,Li, Fu-Mian,Arase, Shinya,Takeoka, shinji,Tsuchide, Eishun
, p. 2199 - 2202 (1994)
A lithocholic acid derivative having high compatibility with phospholipid was synthesized and incorporated to the phospholipid bilayer membrane.A significant influennce of it on the molecular packing and the stability enhancement of the vesicle suspension were clarified by a fluorescence depolarization method and a turbidity measurement, respectively.
Synthesis and proteasome inhibition of lithocholic acid derivatives
Dang, Zhao,Lin, Andrew,Ho, Phong,Soroka, Dominique,Lee, Kuo-Hsiung,Huang, Li,Chen, Chin-Ho
supporting information; experimental part, p. 1926 - 1928 (2011/05/02)
A new class of proteasome inhibitors was synthesized using lithocholic acid as a scaffold. Modification at the C-3 position of lithocholic acid with a series of acid acyl groups yielded compounds with a range of potency on proteasome inhibition. Among the
Lithocholic acid analogues, new and potent α-2,3-sialyltransferase inhibitors
Chang, Kai-Hsuan,Lee, Lenselot,Chen, Jessica,Li, Wen-Shan
, p. 629 - 631 (2008/02/10)
A new type of noncompetitive α-2,3-sialyltransferase inhibitor has been synthesized; we report the discovery, preparation and inhibitory activity of sixteen lithocholic acid analogues. The Royal Society of Chemistry 2006.
