878811-47-3

Upstream product

• 1271-47-2 ferroceneacetylene 
• 622-79-7 benzyl azide 
• 100-39-0 benzyl bromide 

Downstream Products

• 1421681-95-9 1-benzyl-3-methyl-4-ferrocenyl-1H-1,2,3-triazolium tetrafluoroborate 

Relevant academic research and scientific papers

Alkyne-azide cycloadditions with copper powder in a high-pressure continuous-flow reactor: High-temperature conditions versus the role of additives

A safe and efficient flow-chemistry-based procedure is presented for 1,3-dipolar cycloaddition reactions between organic azides and acetylenes. This simple and inexpensive technique eliminates the need for costly special apparatus and utilizes Cu powder a

Mn-Catalyzed 1,6-conjugate addition/aromatization of: Para -quinone methides

A series of ferrocenyl triazole ligands have been synthesized and characterized, which proved to be effective for the Mn-catalyzed 1,6-conjugate addition/aromatization of para-quinone methides with good to high yields under mild conditions. This protocol provided an efficient and practical route to the synthetically interesting functionalized quinones, methines and their analogues.

Dual roles of substituted thiourea as reductant and ligand in CuAAC reaction

A highly efficient catalytic system, CuSO4·5H2O/1-(4-methoxyphenyl)-3-phenylthiourea, for the copper(I)-catalyzed azide–alkyne cycloaddition reaction (CuAAC) was discovered. In the above catalytic system, substituted thiourea acts both as a reductant and a ligand. CuSO4·5H2O/1-(4-methoxyphenyl)-3-phenylthiourea is both an economical and efficient catalyst for the CuAAC reaction. In addition, the new catalytic system has advantageous features including mild and green reaction conditions, and broad substrate compatibility. A variety of 1,4-disubstituted 1,2,3-triazoles have been prepared with good to excellent yields with the CuSO4·5H2O/1-(4-methoxyphenyl)-3-phenylthiourea catalytic system in aqueous solution.

An efficient Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction in aqueous medium with a zwitterionic ligand, betaine

Cu-catalyzed azide-alkyne cycloaddition reaction in aqueous medium was dramatically accelerated by a simple zwitterionic additive, betaine, at ambient temperature. In the presence of betaine, 1,4-disubstituted-1,2,3-triazoles were obtained from azides and

Design and Applications of an Efficient Amphiphilic "click" CuI Catalyst in Water

The copper(I)-catalyzed azide alkyne cycloaddition (CuAAC) using the conventional Sharpless-Fokin catalyst that consists of CuSO4 + Na ascorbate, the most well-known and used "click" reaction, is considerably accelerated by the addition of a tr

Highly efficient click reaction on water catalyzed by a ruthenium complex

The highly efficient click reaction between terminal alkynes and azides has been achieved on water using ruthenium complex RuH2(CO)(PPh3)3 as the catalyst, and the catalyst loading was decreased to 0.2 mol% on water from 5

In Situ Construction of Three Anion-Dependent Cu(I) Coordination Networks as Promising Heterogeneous Catalysts for Azide-Alkyne "Click" Reactions

Three Cu(I) coordination networks, namely, {[Cu2(bpz)2(CN)X]·CH3CN}n, (X = Cl, 1; I, 3), {[Cu6(bpz)6(CH3CN)3(CN)3Br]·2OH·14CH3CN}n, (2

Oximinoalkylamines as ligands for Cu-assisted azide-acetylene cycloaddition

Oximinoalkylamines were found to be efficient ligands for acceleration of the CuAAC reaction. 'Mixed' oxime-triazole ligands TzβOx2 and Tz2βOx demonstrate an approximately 10-fold enhanced acceleration effect co

A layered double hydroxide, a synthetically useful heterogeneous catalyst for azide?alkyne cycloadditions in a continuous-flow reactor

A Cu(II)Fe(III)-layered double hydroxide is shown to efficiently catalyze 1,3-dipolar cycloadditions of organic azides to alkynes leading to valuable 1,2,3-triazoles. The benefits of continuous processing were exploited for reaction optimization and synth

A highly active and magnetically recoverable tris(triazolyl)-CuI catalyst for alkyne-azide cycloaddition reactions

Nanoparticle-supported tris(triazolyl)-CuBr, with a diameter of approximately 25 nm measured by TEM spectroscopy, has been easily prepared, and its catalytic activity was evaluated in the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. In in