87894-56-2Relevant academic research and scientific papers
Alkenylation of 1-Acylindoles with Olefins Bearing Electron-withdrawing Substituents and Palladium Acetate
Itahara, Toshio,Ikeda, Mizue,Sakakibara, Tsutomu
, p. 1361 - 1363 (2007/10/02)
The oxidation of 1-(2,6-dichlorobenzoyl)indole with olefins, such as alkyl acrylates and acrylonitrile, and palladium acetate resulted in selective 3-alkenylation of the indole nucleus.Treatment of 1-acyl-3-methylindoles under similar conditions gave the corresponding 2-alkenyl substituted indoles, while the oxidation of 6-oxo-6H-isoindoloindole gave the corresponding 3-alkenyl substituted indoles.
