87894-65-3

Basic information

• Product Name: 3-ACETOXY-3-METHYLPENTANE-1,5-DIOIC ACID ANHYDRIDE
• Synonyms: 3-ACETOXY-3-METHYLPENTANE-1,5-DIOIC ACID ANHYDRIDE;4-(Acetyloxy)dihydro-4-Methyl-
• CAS NO: 87894-65-3
• Molecular Formula: C₈H₁₀O₅
• Molecular Weight: 186.162
• Product Categories: Miscellaneous Reagents;Heterocycles
• Mol File: 87894-65-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 79-81°C
• Appearance: /
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Acetone, Chloroform
• CAS DataBase Reference: 3-ACETOXY-3-METHYLPENTANE-1,5-DIOIC ACID ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETOXY-3-METHYLPENTANE-1,5-DIOIC ACID ANHYDRIDE(87894-65-3)
• EPA Substance Registry System: 3-ACETOXY-3-METHYLPENTANE-1,5-DIOIC ACID ANHYDRIDE(87894-65-3)

Safety Data

• Hazardous Substances Data: 87894-65-3(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Upstream product

• 503-49-1 meglutol 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 25201-40-5 1,1-diallylethanol 
• 73489-84-6 3-hydroxy-3-methyl-glutaric acid diethyl ester 

Downstream Products

• 2381-87-5 4-methyl-5,6-dihydro-2H-pyran-2-one 
• 78501-60-7 mevalonic acid 5-acetate 
• 674-26-0 mevalonolactone 
• 481-74-3 Chrysophanol 
• 476-56-2 islandicin 
• 67116-19-2 3-methyl-pentenedioic acid anhydride 

Relevant articles and documents

A gas-liquid chromatographic method for steric analysis of 2-hydroxy, 3-hydroxy, and 2,3-dihydroxy acids

A method was developed for assignment of the absolute configuration of oxylipin-derived 2-hydroxy acids, 3-hydroxy acids and 2,3-dihydroxy acids.The monohydroxy acids were converted into diastereomeric N-(propionoxyacyl)-L-phenylalanine-methyl ester (PAP) derivatives by coupling to the methyl ester of L-phenylalanine followed by propionylation, whereas 2,3-dihydroxy acids were derivatized by treatment with L-phenylalanine methyl ester followed by acetone and perchloric acid, to afford diastereomeric N-(2,3-isopropylidenedioxyacyl)-L-phenylalanine methyl ester (IAP) derivatives.The PAP and IAP derivatives were readily resolved by capillary gas-liquid chromatography.In addition, the method described allowed steric analysis of 3-hydroxy-3-methylheptanoic acid, a branched chain hydroxy acid derived from the prostaglandin analogue, misoprostol. - Keywords: Hydroxy acid; Phenylalanine; Steric analysis; Gas-liquid chromatography

SYNTHESIS OF SUBSTITUTED BENZENOIDS AND BIPHENYLS VIA DIELS-ALDER CYCLOADDITION OF 6-METHOXY-2-PYRONES

A convenient synthesis of substituted 6-methoxy-2-pyrones from alkyl and aryl esters is described.These pyrones undergo Diels-Alder reactions with acetylenic dienophiles to provide an efficient route to polysubstituted benzoates, phthalates and biphenyls.

Studies on a Synthesis of (RS)-Mevalonic Acid Lactone

Full details of a high yielding synthesis of mevalonic acid lactone (1) which is of particular value in the preparation of 3- and/or 3'-labelled compounds are described.The key step, conversion of 3-hydroxy-3-methylpentane-1,5-dioic acid (3) into 3-hydroxy-3-methylpentane-1,5-dioic anhydride (4) using acetic anhydride, has been fully investigated, and an additional method using acetyl chloride and triethylamine is described.