879-52-7

Basic information

• Product Name: α-Phenylthiazole-2-methanol
• Synonyms: α-Phenyl-2-thiazolemethanol;α-Phenylthiazole-2-methanol
• CAS NO: 879-52-7
• Molecular Formula: C₁₀H₉NOS
• Molecular Weight: 191.25
• Mol File: 879-52-7.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-Phenylthiazole-2-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: α-Phenylthiazole-2-methanol(879-52-7)
• EPA Substance Registry System: α-Phenylthiazole-2-methanol(879-52-7)

Safety Data

• Hazardous Substances Data: 879-52-7(Hazardous Substances Data)

Upstream product

• 40610-14-8 2-lithiothiazole 
• 100-52-7 benzaldehyde 
• 3034-53-5 2-bromo-1,3-thiazole 
• 134271-25-3 [1-Phenyl-1-thiazol-2-yl-meth-(E)-ylidene]-hydrazine 
• 134271-25-3 [1-Phenyl-1-thiazol-2-yl-meth-(Z)-ylidene]-hydrazine 
• 7210-75-5 1,3-Thiazol-2-yl phenyl ketone 
• 21314-17-0 4-hydroxy-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 10200-59-6 Thiazole-2-carbaldehyde 
• 5334-48-5 4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine 
• 380303-38-8 diisopropyl-carbamic acid phenyl-thiazol-2-yl-methyl ester 
• 288-47-1 1,3-thiazole 
• 79265-30-8 2-(trimethylsilyl)thiazole 
• 87636-27-9 2-(Phenyl-trimethylsilanyloxy-methyl)-thiazole 
• 134271-27-5 3-Phenyl-1,2,3-triazolo<5,1-b>thiazole 

Downstream Products

• 7210-75-5 1,3-Thiazol-2-yl phenyl ketone 
• 134271-31-1 2-(Dibromo-phenyl-methyl)-thiazole 
• 134271-27-5 3-Phenyl-1,2,3-triazolo<5,1-b>thiazole 
• 134271-25-3 [1-Phenyl-1-thiazol-2-yl-meth-(Z)-ylidene]-hydrazine 
• 134271-25-3 [1-Phenyl-1-thiazol-2-yl-meth-(E)-ylidene]-hydrazine 
• 93001-83-3 2-(α-Phenylacetoxymethyl)thiazole 
• 132499-96-8 BTNPHTS 
• 133543-90-5 3-(2-thiazolylcarbonyl)benzenesulfonic acid 
• 717121-63-6 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol 
• 433924-26-6 2-[allyloxy(phenyl)methyl]thiazole 

Relevant articles and documents

Asymmetric Hydroboration of Heteroaryl Ketones by Aluminum Catalysis

A series of methyl aluminum complexes bearing chiral biphenol-type ligands were found to be highly active catalysts in the asymmetric reduction of heterocyclic ketones (S/C = 100-500, ee up to 99%). The protocol is suitable for a wide range of substrates and has a high tolerance to functional groups. The formed 2-heterocyclic-alcohols are valuable building blocks in drug discovery or can be used as ligands in asymmetric catalysis. Isolation and comprehensive characterization of the reaction intermediates support a catalysis cycle proposed by DFT calculations.

Ruthenium catalyzed hydrohydroxyalkylation of isoprene with heteroaromatic secondary alcohols: Isolation and reversible formation of the putative metallacycle intermediate

Heteroaromatic secondary alcohols react with isoprene to form products of hydrohydroxyalkylation in the presence of ruthenium(0) catalysts generated from Ru3(CO)12 and tricyclohexylphosphine, enabling direct conversion of secondary to tertiary alcohols in the absence of premetalated reagents or stoichiometric byproducts. The putative oxaruthenacycle intermediate has been isolated and characterized, and reversible metallacycle formation has been demonstrated.

Preparation and use of magnesium amides

The present application relates to mixed Mg/Li amides of the general formula ???????? R1R2N-MgX·zLiY?????(I), wherein R1, R2 and R3 independently are selected from substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or derivatives thereof, and, for R1 and R2 only, the silyl derivatives thereof; one of R1 and R2 may be H; or R1 and R2 together can be part of a cyclic or polymeric structure; X and Y independently are selected amongst others from the group consisting of F; Cl; Br; I; CN; SCN; NCO; and z > 0, as well as a process for the preparation of the mixed Mg/Li amides and the use of these amides, e.g. as bases.