879220-82-3Relevant academic research and scientific papers
Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides
Narumi, Tetsuo,Tomita, Kenji,Inokuchi, Eriko,Kobayashi, Kazuya,Oishi, Shinya,Ohno, Hiroaki,Fujii, Nobutaka
, p. 3465 - 3468 (2007)
Chemo- and stereoselective synthesis of fluoroalkenes was achieved in excellent yields via Pd-catalyzed C-F bond activation. In this transformation, Et3N plays a crucial role to produce reactive hydride species such as Ph(EtO)SiH2 an
Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1
Niida, Ayumu,Tomita, Kenji,Mizumoto, Makiko,Tanigaki, Hiroaki,Terada, Tomohiro,Oishi, Shinya,Otaka, Akira,Inui, Ken-Ichi,Fujii, Nobutaka
, p. 613 - 616 (2007/10/03)
Described is a novel synthetic route for dipeptide isosteres containing (Z)-alkene and (E)-fluoroalkene units as cis-amide bond equivalents via organocopper-mediated reduction of γ-acetoxy- or γ,γ-difluoro- α,β-unsaturated-δ-lactams. The synthesized isost
