87931-47-3

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 79672-56-3 ethyl 3-hydroxy-3-(4-methoxyphenyl)butanoate 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 124-38-9 carbon dioxide 
• 89619-03-4 2-(4-methoxyphenyl)allylalcohol 

Downstream Products

• 1428266-90-3 1-(4,4-difluoro-4-(phenylsulfonyl)but-1-en-2-yl)-4-methoxybenzene 
• 1254470-57-9 N-[2-(4-methoxyphenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide 
• 124-38-9 carbon dioxide 
• 1712-69-2 1-isopropenyl-4-methoxybenzene 
• 3516-65-2 4-(4-methoxyphenyl)furan-2(5H)-one 
• 1374016-22-4 N-[2-(4-methoxyphenyl)prop-2-en-1-yl]-N,N-bis(p-toluenesulfonyl)imide 

Relevant academic research and scientific papers

Highly Regioselective Palladium-Catalyzed Carboxylation of Allylic Alcohols with CO2

Various allylic alcohols were carboxylated in the presence of a catalytic amount of PdCl2 and PPh3 using ZnEt2 as a stoichiometric transmetalation agent under a CO2 atmosphere (1atm). This carboxylation proceeded in a highly regioselective manner to afford branched carboxylic acids predominantly. The β,γ-unsaturated carboxylic acid thus obtained was successfully converted into an optically active γ-butyrolactone, a known intermediate of (R)-baclofen.

Copper-catalyzed difluoromethylation of β,γ-unsaturated carboxylic acids: An efficient allylic difluoromethylation

Not one but two! A new strategy for the regiospecific construction of compounds with allylic CF2H groups has been developed. The decarboxylative (phenylsulfonyl)difluoromethylation of β,γ- unsaturated carboxylic acids is catalyzed by a Lewis acid (CuCl 2·2 H2O), and the resulting product easily undergoes desulfonylation. Copyright

Rh-catalyzed highly enantioselective synthesis of 3-arylbutanoic acids

(Chemical Equation Presented) It's in the mix: The reaction conditions - catalyst, additive, and solvent - have been optimized for the asymmetric hydrogenation of 3-aryl-3-butenoic acids. The rigid, chiral bisphospholane ligand (SP,RC)-DuanPhos is crucial to achieving high enantioselectivity.

3-Aryl-3-butenoic Acids and Their Esters: Practical Synthesis from Diketene by the Palladium-Catalyzed Grignard Coupling Reaction and Application as Monomers for the Radical Copolymerization with Styrene

Treatment of arylmagnesium bromide with an equimolar amount of zinc chloride followed by the reaction with diketene in the presence of a catalytic amount of PdCl2(PPh3)2 provided an improved synthetic method for 3-aryl-3-butenoic acid in a large scale.App

Studies in Decarboxylation. Part 16. Steric Inhibition of Resonance in a 1,5-Sigmatropic Reaction

The rates of gas-phase decarboxylation of some 3-phenyl-substituted but-3-enoic acids are best rationalized in terms of steric inhibition of resonance in the more sterically crowded members.