879573-84-9Relevant articles and documents
A new approach to the synthesis of lamotrigine and other 3,5-diamino-1,2,4-triazine derivatives
Ulomskii,Shestakova,Deev,Rusinov,Chupakhin
, p. 726 - 732 (2007/10/03)
A new in principle method for the synthesis of 6-aryl(hetaryl)-3,5-diamino- 1,2,4-triazines by decomposition of pre-synthesized tetrazolo[1,5-b][1,2,4] triazines was developed. The advantages of this method over traditional methods were demonstrated using the synthesis of a modern antiepileptic preparation lamotrigine, as an example.