87967-98-4Relevant academic research and scientific papers
Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter
Steiger, Scott A.,Li, Chun,Backos, Donald S.,Reigan, Philip,Natale
, p. 3223 - 3234 (2017/05/29)
A series of dimeric isoxazolyl-1,4-dihydropyridines (IDHPs) were prepared by click chemistry and examined for their ability to bind the multi-drug resistance transporter (MDR-1), a member of the ATP-binding cassette superfamily (ABC). Eight compounds in t
NEUTRAL DICHROMATE OXIDATION. PREPARATION AND UTILITY OF ISOXAZOLE ALDEHYDES
Natale, Nicholas R.,Quincy, David A.
, p. 817 - 822 (2007/10/02)
Isoxazole alcohols 1 can be oxidized by potassium dichromate in neutral organic media to give the corresponding aldehydes, 2 without destruction of the isoxazole ring.Isoxazole aldehydes 2 are of utility as starting materials for 4-(4'-isoxazyl)-1,4-dihydropyridines 3.
