879899-84-0Relevant articles and documents
Conformational arm-wrestling: Battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents
Clayden, Jonathan,Foricher, Yann J. Y.,Helliwell, Madeleine,Johnson, Paul,Mitjans, David,Vinader, Victoria
, p. 444 - 454 (2008/01/27)
The orientation of a tertiary amide group adjacent to an aromatic ring may be governed by the stereochemistry of an adjacent chiral substituent. With a chiral substituent in both ortho positions, matched/mismatched pairs of isomers result. Evidence for ma