880-93-3

Basic information

• Product Name: 1-METHYL-4-NITRONAPHTHALENE
• Synonyms: 1-METHYL-4-NITRONAPHTHALENE;4-Methyl-1-nitronaphthalene;Naphthalene, 1-methyl-4-nitro-
• CAS NO: 880-93-3
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19
• Mol File: 880-93-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 71.5°C
• Boiling Point: 321.94°C (rough estimate)
• Flash Point: 165°C
• Appearance: /
• Density: 1.1963 (rough estimate)
• Vapor Pressure: 0.000203mmHg at 25°C
• Refractive Index: 1.4900 (estimate)
• CAS DataBase Reference: 1-METHYL-4-NITRONAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-4-NITRONAPHTHALENE(880-93-3)
• EPA Substance Registry System: 1-METHYL-4-NITRONAPHTHALENE(880-93-3)

Safety Data

• Hazardous Substances Data: 880-93-3(Hazardous Substances Data)

Usage

Uses

1-Methyl-4-nitronaphthalene is used in preparation of S-triazolyl α-mercaptoacetanilides as inhibitors of HIV reverse transcriptase.

InChI:InChI=1/C11H9NO2/c1-8-6-7-11(12(13)14)10-5-3-2-4-9(8)10/h2-7H,1H3

Upstream product

• 7446-70-0 aluminium trichloride 
• 625-58-1 ethyl nitrate 
• 90-12-0 1-Methylnaphthalene 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 103986-53-4 4-methyl-1-naphthylboronic acid 
• 108-24-7 acetic anhydride 
• 624-91-9 methyl nitrite 

Downstream Products

• 1975-43-5 4-nitro-1-naphthoic acid 
• 4523-45-9 1-amino-4-methylnaphthalene 
• 61757-43-5 4-amino-1-naphthaldehyde 
• 108450-99-3 4-Methyl-1-nitro-2-(p-tolylsulfonylmethyl)naphthalene 
• 4523-52-8 1-dimethylamino-4-methylnaphthalene 
• 51670-78-1 1-acetamido-4-methylnaphthalene 
• 20601-22-3 2-bromo-1-methylnaphthalene 

Relevant articles and documents

1,4-SUBSTITUTED ISOQUINOLINE INHIBITORS OF KEAP1/NRF2 PROTEIN-PROTEIN INTERACTION

Disclosed herein are compounds that can act as inhibitors of the Kelch-like ECH- associated protein 1/nuclear factor (erythroid-derived 2)-like 2 ("KEAP1/NRF2") protein- protein interaction, and methods of using the compounds to treat and prevent diseases and disorders, such as COPD, multiple sclerosis, and diabetes, and in the promotion of wound healing. The compounds described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: formula (I), wherein the substituents are as described.

Green and controllable metal-free nitrification and nitration of arylboronic acids

A novel and green nitrating reagent has been developed for the nitrification and nitration of arylboronic acids, which can be controlled by the reaction conditions. The process provides an attractive alternative to the traditional nitration protocols.

Aromatic nitration in liquid Ag0.51K0.42Na 0.07NO3

(Figure Presented) Aromatic molecules have a strong affinity for silver(I) and dissolve to a limited extent in Ag0.51K0.42Na 0.07NO3, a low-melting eutectic mixture of silver, potassium, and sodium nitrates. Aromatic nitration in this inorganic ionic liquid leads to products which arise from nonelectrophilic substitution pathways.