88013-55-2Relevant academic research and scientific papers
Synthesis and antidepressant activity of 4-aryltetrahydrothieno[2,3-c]pyridine derivatives
Schneider,Weber,Daniel,Bechtel,Boeke-Kuhn
, p. 1150 - 1155 (2007/10/02)
A series of substituted 4-aryltetrahydrothieno[2,3-c]pyridines was prepared by acid-catalyzed cyclization of 1-aryl-2-[(2-thienylmethyl)amino]ethanol derivatives. The compounds were examined for their antidepressant activity, as demonstrated by their abil
4-Phenyl-4,5,6,7-tetrahydro-thieno [2,3-c]pyridines, compositions and use
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 is amino, acetylamino, hydroxymethyl, methoxymethyl or STR2 R2 and R3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl; R4 is straight or branched alkyl of 1 to 3 carbon atoms; and R5 and R6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH2 -group in the ring may be replaced by an oxygen atom, and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.
