880144-50-3

Basic information

• Product Name: 2-[(6S,9R)-9-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-3-yl]propan-2-ol
• Synonyms: 2-[(6S,9R)-9-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-3-yl]propan-2-ol
• CAS NO: 880144-50-3
• Molecular Weight: 321.37
• Mol File: 880144-50-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[(6S,9R)-9-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-3-yl]propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(6S,9R)-9-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-3-yl]propan-2-ol(880144-50-3)
• EPA Substance Registry System: 2-[(6S,9R)-9-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-3-yl]propan-2-ol(880144-50-3)

Safety Data

• Hazardous Substances Data: 880144-50-3(Hazardous Substances Data)

Upstream product

• 880144-49-0 tert-butyl [(6S,9R)-6-(2,3-difluorophenyl)-3-(1-methoxy-1-methylethyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-9-yl]carbamate 
• 880144-46-7 tert-butyl (3R,6S)-6-(2,3-difluorophenyl)-2-thioxoazepan-3-ylcarbamate 
• 885033-77-2 1-amino-3-hydroxy-3-methylbutan-2-one hydrochloride 
• 885032-39-3 di-tert-butyl (3-hydroxy-3-methyl-2-oxobutyl)imidodicarbonate 
• 1236226-80-4 1-amino-3-methyl-2,3-butanediol 
• 781650-32-6 tert-butyl [(3R,6S)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]carbamate 
• 870-63-3 prenyl bromide 
• 115270-03-6 1--3-methyl-2-butene 
• 885032-74-6 tert-butyl (6S,9R)-6-(2,3-difluorophenyl)-3-(1-hydroxy-1-methylethyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-9-ylcarbamate 

Downstream Products

• 885030-22-8 C₂₉H₃₂F₂N₆O₄ 

Relevant articles and documents

Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: Discovery of MK-2918

In our ongoing efforts to develop CGRP receptor antagonists for the treatment of migraine, we aimed to improve upon telecagepant by targeting a compound with a lower projected clinical dose. Imidazoazepanes were identified as potent caprolactam replacemen