880152-28-3 Usage
Molecular structure
The compound has a complex structure that includes a cyclohexene ring, a long carbon chain, an amine group, and a silyl ether group.
Functional groups
The compound contains a hydroxyl group (-OH), an amine group (-NH2), and a silyl ether group (-Si).
Stereochemistry
The compound has a (3R) configuration at the 3rd carbon of the butyl side chain.
Ester functional group
The compound is an ester, specifically an acetate ester, formed by the reaction of the hydroxyl group of 1-Cyclohexene-1-methanol with acetic acid.
Reactivity
The compound is versatile in its reactivity due to the presence of the amine and silyl ether groups, making it useful for various chemical reactions.
Protecting group
The silyl ether group serves as a protecting group for hydroxyl groups in organic synthesis.
Potential applications
The compound has potential use in organic synthesis, medicinal chemistry, and material science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 880152-28-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,0,1,5 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 880152-28:
(8*8)+(7*8)+(6*0)+(5*1)+(4*5)+(3*2)+(2*2)+(1*8)=163
163 % 10 = 3
So 880152-28-3 is a valid CAS Registry Number.
880152-28-3Relevant academic research and scientific papers
Aza-[3 + 3] annulations. Part 6. Total syntheses of putative (-)-lepadiformine and (-)-cylindricine C
Wang, Jiashi,Swidorski, Jacob J.,Sydorenko, Nadiya,Hsung, Richard P.,Coverdale, Heather A.,Kuyava, Jennifer M.,Liu, Jia
, p. 423 - 459 (2007/10/03)
Efforts in achieving an enantioselective total synthesis of (-)-cylindricine C along with the syntheses of putative lepadiformine, epi-lepadiformines, (-)-4-deoxo-cylindricine C, and (-?-2-epi-cylindricine C are described here in details. These syntheses feature a stereoselective intramolecular aza-[3 + 3] annulation as a unified strategy, and specifically, the total synthesis of (-)-cylindricine C was accomplished in 22 steps with a 4.5% overall yield from L-serine. In addition, we developed an interesting halohydrin formation for the construction of the C4-ketone of cylindricines.
A concise total synthesis of (-)-cylindricine C through a stereoselective intramolecular aza-[3 + 3] annulation strategy
Swidorski, Jacob J.,Wang, Jiashi,Hsung, Richard P.
, p. 777 - 780 (2007/10/03)
An enantioselective total synthesis of (-)-cylindricine C is described, featuring a diastereoselective intramolecular aza-[3 + 3] annulation strategy and an interesting halohydrin formation of the C4-5 olefin for construction of C4-ketone. This work provi
