880343-42-0

Basic information

• Product Name: chloro-tetramethyl-phosphorane
• Synonyms: chloro-tetramethyl-phosphorane
• CAS NO: 880343-42-0
• Molecular Weight: 126.566
• Mol File: 880343-42-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: chloro-tetramethyl-phosphorane(CAS DataBase Reference)
• NIST Chemistry Reference: chloro-tetramethyl-phosphorane(880343-42-0)
• EPA Substance Registry System: chloro-tetramethyl-phosphorane(880343-42-0)

Safety Data

• Hazardous Substances Data: 880343-42-0(Hazardous Substances Data)

Upstream product

• 74-87-3 methylene chloride 
• 7803-51-2 phosphan 
• 75-09-2 dichloromethane 
• 594-09-2 trimethylphosphane 
• 917-64-6 methyl magnesium iodide 
• 7719-12-2 phosphorus trichloride 

Relevant articles and documents

Synthesis of Primary and Secondary Phosphines by Selective Alkylation of PH3 under Phase Transfer Conditions

Primary phosphines, RPH2, may be synthesized selectively by alkylation of phosphine, PH3, with alkyl halides RX (R = Me, Et, n-Bu, 2-Bu, C16H33, CH2=CH-CH2, Ph-CH2, 2-Py-CH2-CH2; X = Cl, Br) and concentrated aqueous KOH as auxilliary base in dimethylsulfoxide as a solvent or in two phase systems employing phase transfer catalysts.Under more rigorous conditions secondary phosphines R2PH (R = Me, n-Bu, CH2=CH-CH2) are also acessible in good yields.Using 1,3-dibromo(chloro)-propane or -butane diprimary phosphines H2P-(CH2)2-CHR-PH2 (R = H, Me) are obtaines, while 1,4-dibromopentane in a high yield cyclization reaction leads to 2-methylphospholane (12) with a chiral C-atom in α-position.