88037-86-9Relevant academic research and scientific papers
Antibiotics from Algae, 38. - Base-Catalyzed Reactions of Multiple Hydroxylated Diphenyl Ethers
Glombitza, Karl-Werner,Woelwer-Rieck, Ursula
, p. 261 - 266 (2007/10/02)
Diphenyl ethers are in general difficult to cleave.Under certain conditions in a weak alkaline aqueous solution multiple hydroxylated diphenyl ethers are brought to reaction.It is shown at 33 model substances which substitution pattern must be present in
Isolation, Structure Determination, and Total Synthesis of the Dibenzofurans α- and β-Pyrufuran, New Phytoalexins from the Wood of Pyrus communis L.
Kemp, Malcolm S.,Burden, Raymond S.,Loeffler, R. S. Thomas
, p. 2267 - 2272 (2007/10/02)
The antifungal compounds α- and β-pyrufuran have been isolated from the wood of perry pear trees infected with Chondrostereum purpureum (Pers. ex Fr.) Pouzar, the causative fungus of silver leaf disease.Spectroscopic and chemical evidence show that the compounds are 1,2,3,4-substituted trimethoxydibenzofuranols.Three of the four possible positional isomers, compounds (11), (12), and (13), have been synthesized by cyclisation of the corresponding trimethoxydiphenyl ethers using palladium (II) acetate, followed by oxidation of the organo-lithium derivative using lithium t-butyl peroxide.The latter stage proved unsuccessful in the attempted synthesis of 2,3,4-trimethoxydibenzofuran-1-ol (10).Comparison of spectroscopic and chromatographic properties of the natural products and synthesized compounds show α-pyrufuran and β-pyrufuran to be 1,3,4-trimethoxydibenzofuran-2-ol (11) and 1,2,4-trimethoxydibenzofuran-3-ol (12), respectively.
