88039-96-7

Basic information

• Product Name: 6-chloro-3-phenyl-2H-chromen-2-one
• Synonyms: 6-chloro-3-phenyl-2H-chromen-2-one
• CAS NO: 88039-96-7
• Molecular Formula: C₁₅H₉ClO₂
• Molecular Weight: 256.68376
• Mol File: 88039-96-7.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-chloro-3-phenyl-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-3-phenyl-2H-chromen-2-one(88039-96-7)
• EPA Substance Registry System: 6-chloro-3-phenyl-2H-chromen-2-one(88039-96-7)

Safety Data

• Hazardous Substances Data: 88039-96-7(Hazardous Substances Data)

Upstream product

• 114-70-5 sodium phenylacetate 
• 635-93-8 5-chlorosalicyclaldehyde 
• 140-29-4 phenylacetonitrile 
• 536-74-3 phenylacetylene 
• 1333483-14-9 N-methyll-N-(phenylethylnyl)methanesulfonamide 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 100-44-7 benzyl chloride 
• 7436-90-0 2,2-dibromostyrene 
• 103-82-2 phenylacetic acid 
• 2051-59-4 6-Chloro-chromen-2-one 
• 71-43-2 benzene 
• 201230-82-2 carbon monoxide 
• 1004-99-5 2-chloro-2-phenylethanol 

Downstream Products

• 13130-28-4 6-chloro-3-(2-hydroxyphenyl)-2H-chromen-2-one 
• 1404301-76-3 2-(2-(1,3-dithian-2-ylidene)-2-phenylethyl)-4-chlorophenol 
• 1404301-60-5 6-chloro-3-phenylhydrocoumarin 
• 1404301-95-6 (S)-6-chloro-3-phenylspiro[chroman-2,2'-[1,3]dithiane] 

Relevant articles and documents

Zn(II)-Catalyzed One-Pot Synthesis of Coumarins from Ynamides and Salicylaldehydes

A highly efficient and straightforward synthesis of diversely substituted coumarins from ynamides and salicylaldehydes in the presence of Zn(II) catalyst has been developed. The sulfonamide moiety of ynamides was successfully recycled in this process, serving as an effective traceless directing group for high regioselectivity in the bond-forming event. The advantages of this protocol are good functional group tolerance, broad substrate scope, simple and high-yielding reaction, recovery/reuse of the sulfonamides, low catalyst loading of inexpensive catalyst, and, by these merits, a more cost-effective and greener process.

A complete switch of the directional selectivity in the annulation of 2-hydroxybenzaldehydes with alkynes

Controlling reaction selectivity is an eternal pursuit for chemists working in chemical synthesis. As part of this endeavor, our group has been exploring the possibility of constructing different natural product skeletons from the same simple starting mat

Monoamine oxidase (MAO) inhibitory activity: 3-phenylcoumarins versus 4-hydroxy-3-phenylcoumarins

Monoamine oxidase (MAO) is a useful target in the treatment of neurodegenerative diseases and depressive disorders. Both isoforms, MAO-A and MAO-B, are known to play critical roles in disease progression, and as such, the identification of novel, potent a