880461-84-7Relevant academic research and scientific papers
The Mannich-type reaction between N,O-acetals and carbon nucleophiles under solvent-free conditions
Matsumura, Yoshihiro,Ikeda, Takashi,Onomura, Osamu
, p. 113 - 117 (2006)
The Mannich-type reaction for 1-methoxycarbonyl- or 1-benzyloxy-carbonyl-2-methoxylpyrrolidine with carbon nucleophiles such as acetylacetone, methyl acetoacetate, dimethyl malonates, benzoylacetone, dibenzoylmethane, or cyclohexane-1, 3-dione proceeded b
Synthesis of bicyclic guanidines from pyrrolidin-2-one
Louwrier, Saskia,Tuynman, Antonin,Hiemstra, Henk
, p. 2629 - 2646 (2007/10/03)
The syntheses of three bicyclic guanidines as model compounds for the guanidine alkaloid ptilomycalin A are described. The guanidines are prepared from pyrrolidin-2-one via an N-acyliminium ion coupling reaction with silyl enol ethers and a direct guanylation with bis-Boc-thiourea and HgCl2 as the key steps.
