880596-94-1Relevant academic research and scientific papers
Synthesis and cell-based activity of a potent and selective protein tyrosine phosphatase 1B inhibitor prodrug
Boutselis, Irene G.,Yu, Xiao,Zhang, Zhong-Yin,Borch, Richard F.
, p. 856 - 864 (2007/10/03)
Our laboratory recently reported the development of novel prodrug chemistry for the intracellular delivery of phosphotyrosine mimetics. This chemistry has now been adapted for the synthesis of a prodrug that delivers the nonhydrolyzable difluoromethylphos
PRODRUGS OF DRUG-PHOSPHATE CONJUGATES AND ANALOGS THEREOF
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Page/Page column 33, (2010/10/20)
Phosphate-substituted therapeutic compounds and analogs thereof that may serve as prodrugs are described. The prodrugs may include phosphorus-containing compounds, drug-phosphate conjugates, and analogs of drug-phosphate conjugates. Also described are ana
