880870-13-3

Basic information

• Product Name: 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE
• Synonyms: 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE
• CAS NO: 880870-13-3
• Molecular Formula: C₆H₅BrClNO
• Molecular Weight: 222.47
• Mol File: 880870-13-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 251℃
• Flash Point: 105℃
• Appearance: /
• Density: 1.650
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.14±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE(880870-13-3)
• EPA Substance Registry System: 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE(880870-13-3)

Safety Data

• Hazardous Substances Data: 880870-13-3(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-chloro-4-methoxypyridine is a chemical compound with the molecular formula C6H5BrClNO. It is a pyridine derivative that contains bromine, chlorine, and methoxy functional groups. 5-BROMO-2-CHLORO-4-METHOXYPYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is known for its high reactivity and ability to undergo various chemical reactions, making it a valuable building block in organic synthesis. 5-Bromo-2-chloro-4-methoxypyridine is also used as a reagent in research and industrial laboratories for its versatile properties and potential applications in the development of new compounds.

Upstream product

• 17228-69-2 2-chloro-4-methoxy-pyridine 
• 849937-96-8 5-bromo-2,4,-dichloropyridine 
• 124-41-4 sodium methylate 

Downstream Products

• 1256823-05-8 6-chloro-4-methoxypyridine-3-carbaldehyde 
• 1196146-82-3 5-bromo-2-chloro-pyridin-4-ol 
• 1187190-69-7 6-chloro-4-methoxypyridine-3-carbonitrile 
• 880870-14-4 C₁₃H₁₀Cl₂FNO 

Relevant articles and documents

PLASMA KALLIKREIN INHIBITORS AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.