88116-43-2Relevant academic research and scientific papers
TBHP/CoCl2-mediated intramolecular oxidative cyclization of N-(2-formylphenyl)amides: An approach to the construction of 4H-3,1-benzoxazin-4-ones
Yu, Junchao,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 562 - 568 (2016/02/18)
The intramolecular oxidative cyclization of N-(2-formylphenyl)amides has been realized through an oxidative C(sp2)-O(sp2) bond-forming reaction between an aldehyde carbon and amide oxygen. This new strategy, which uses tert-butyl hydroperoxide (TBHP) as an oxidant and CoCl2 as the catalyst, allows for the efficient Co-catalyzed synthesis of useful benzoxazin-4-one derivatives and features readily available starting materials and mild reaction conditions. The intramolecular cyclization of N-(2-formylphenyl)amides has been realized through an oxidative C(sp2)-O(sp2) bond-forming reaction between an aldehyde carbon and amide oxygen. This new strategy, which uses tert-butyl hydroperoxide (TBHP) as the oxidant and CoCl2 as the catalyst, allows for the efficient Co-catalyzed synthesis of useful benzoxazin-4-one derivatives.
A facile approach for new dibenzo [b,f][1,5] diazocinones
Pessoa-Mahana, Hernan,Martinez Aranguiz, Karen G.,Araya-Maturana, Ramiro,Pessoa-Mahana, C. David
, p. 1493 - 1500 (2007/10/03)
The synthesis of new eight-membered cycle dibenzo[b,f][1,5]-diazocine-6- (5W)-one derivatives 11, 12 was developed. The key step in this synthesis was the intramolecular cyclization of the amino aldehyde precursors 9, 10 obtained by a selective reduction
Metal Template Reactions. XVII. The Attempted Dimerization of Amino Carbonyl Compounds Containing a Supporting Donor Atom
Black, David St. C.,Rothnie, Neil E.
, p. 1149 - 1157 (2007/10/02)
Attempts to effect metal template condensative dimerizations of the amino aldehydes (4), (11) and (12) and the amino ketone (24) have been unsuccessful.Oxidation of the alcohol (9) did not allow isolation of the aldehyde (4).The alcohol (17) underwent oxi
