881673-69-4 Usage
Structure
Ethyl ester derivative of pyrrole-3-carboxylic acid with a methyl and phenyl substitution on the pyrrole ring, and a phenylsulfonyl group attached to the pyrrole ring
Molecular weight
381.44 g/mol
Appearance
Not provided in the material
Solubility
Not provided in the material
Stability
Not provided in the material
Reactivity
Not provided in the material
Functional groups
Ester, pyrrole, methyl, phenyl, and sulfonyl groups
Potential applications
Medicinal chemistry and drug development, used as a building block in the synthesis of pharmaceutical compounds, and may have potential therapeutic effects. Of interest to researchers and scientists in the fields of organic chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 881673-69-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,6,7 and 3 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 881673-69:
(8*8)+(7*8)+(6*1)+(5*6)+(4*7)+(3*3)+(2*6)+(1*9)=214
214 % 10 = 4
So 881673-69-4 is a valid CAS Registry Number.
881673-69-4Relevant articles and documents
Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers
Nishida, Haruyuki,Hasuoka, Atsushi,Arikawa, Yasuyoshi,Kurasawa, Osamu,Hirase, Keizo,Inatomi, Nobuhiro,Hori, Yasunobu,Sato, Fumihiko,Tarui, Naoki,Imanishi, Akio,Kondo, Mitsuyo,Takagi, Terufumi,Kajino, Masahiro
, p. 3925 - 3938 (2012/08/14)
To discover a gastric antisecretory agent more potent than existing proton pump inhibitors, novel pyrrole derivatives were synthesized, and their H +,K+-ATPase inhibitory activities and inhibitory action on histamine-stimulated gastric acid secretion in rats were evaluated. Among the compounds synthesized, compound 17a exhibited selective and potent H +,K+-ATPase inhibitory activity through reversible and K+-competitive ionic binding; furthermore, compound 17c exhibited potent inhibitory action on histamine-stimulated gastric acid secretion in rats and Heidenhain pouch dogs.
