881673-85-4

Basic information

• Product Name: Carbamic acid, methyl[[1-(phenylsulfonyl)-5-(3-thienyl)-1H-pyrrol-3-yl]methyl]-, 1,1-dimethylethyl ester
• CAS NO: 881673-85-4
• Molecular Formula: C21H24N2O4S2
• Molecular Weight: 432.565
• Mol File: 881673-85-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, methyl[[1-(phenylsulfonyl)-5-(3-thienyl)-1H-pyrrol-3-yl]methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, methyl[[1-(phenylsulfonyl)-5-(3-thienyl)-1H-pyrrol-3-yl]methyl]-, 1,1-dimethylethyl ester(881673-85-4)
• EPA Substance Registry System: Carbamic acid, methyl[[1-(phenylsulfonyl)-5-(3-thienyl)-1H-pyrrol-3-yl]methyl]-, 1,1-dimethylethyl ester(881673-85-4)

Safety Data

• Hazardous Substances Data: 881673-85-4(Hazardous Substances Data)

Upstream product

• 6165-69-1 Thien-3-ylboronic acid 
• 881673-84-3 tert-butyl {[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-methyl}methylcarbamate 
• 144-55-8 sodium hydrogencarbonate 
• 2703-17-5 methyl 1H-pyrrole-3-carboxylate 
• 16420-39-6 methyl 5-bromo-1H-pyrrole-3-carboxylate 
• 881673-80-9 methyl 5-bromo-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate 
• 881673-81-0 [5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol 
• 881673-82-1 5-bromo-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde 
• 881673-83-2 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

Proton pump inhibitors which have excellent proton pumping activity and which can be converted in vivo into proton pump inhibitors to exhibit antiulcer effect and so on, containing compounds represented by the general formula (I) or salts thereof or prodrugs of the same: (I) wherein X and Y are each independently a free valency or a spacer whose main chain has 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; R2, R3 and R4 are each independently hydrogen, an optionally substituted hydrocarbon group, optionally substituted thienyl, optionally substituted benzo[b]thienyl, optionally substituted furyl, optionally substituted pyridyl, optionally substituted pyrazolyl, optionally substituted pyrimidinyl, acyl, halogeno, cyano, or nitro; and R5 and R6 are each independently hydrogen or an optionally substituted hydrocarbon group.