881685-58-1Relevant academic research and scientific papers
METHOD FOR PRODUCING PYRAZOLYLCARBOXANILIDES
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Paragraph 0096; 0097, (2014/05/20)
The present invention relates to a simplified process for preparing pyrazolylcarboxanilides by reacting pyrazolylcarboxylic esters with anilines in the presence of a base and removing at least one reaction product.
Method For Manufacturing Aryl Carboxamides
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Page/Page column 4, (2011/04/14)
A process for preparing arylcarboxamides of the formula (I) where Ar =a mono- to trisubstituted phenyl, pyridyl or pyrazolyl ring, where the substituents are selected from halogen, Ci-C4-alkyl and C1-C4-haloalkyl; M =thienyl or phenyl, which may bear a halogen substituent; Q =direct bond, cyclopropylene, fused bicycio[2.2.1]heptane or bicyclo[2.2.1]heptene ring; R1 =hydrogen, halogen, C1-C6-alkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, mono- to trisubstituted phenyl, where the substituents are selected from halogen and trifluoromethylthio, or cyclopropyl; by reacting an acid chloride of the formula (II) with an arylamine (III) in a suitable nonaqueous solvent, wherein, in the absence of an auxiliary base, a) the acid chloride (II) is initially charged, b) a pressure of from 0 to 700 mbar is established, c) the arylamine (III) is metered in in an approximately stoichiometric amount and d) the product of value is isolated.
Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides
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Page/Page column 19, (2010/07/10)
The present invention relates to a process for preparing N-substituted (3-dihalomethylpyrazol-4-yl)carboxamides of the formula (I) in which R1 is optionally substituted phenyl or C3-C7-cycloalkyl, R1a is hydrogen or fluorine, or R1a together with R1 is optionally substituted C3-C5-alkanediyl or C5-C7-cycloalkanediyl, R2 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl or C1-C4-alkoxy-C1-C2-alkyl, X is F or Cl and n is 0, 1, 2 or 3; which comprises A) providing a compound of the formula (II) in which X is F or Cl, Y is Cl or Br and R2 has one of the meanings given above and B) reacting a compound of the formula (II) with carbon monoxide and a compound of the formula (III) in which R1, R1a and n have one of the meanings given above; in the presence of a palladium catalyst; to intermediates used for the preparation according to the process according to the invention, and also to processes for their preparation.
METHODS FOR THE PREPARATION OF FUNGICIDES
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Page/Page column 34; 36, (2010/07/09)
The present invention relates to methods of preparing compounds of formula (I) comprising the step of reacting the corresponding amide with the corresponding substituted aryl in the presence of a catalyst, which catalyst comprises copper and a ligand, Y is CHCHR6(R7) or C=C(A)Z, CY2(R2)Y3(R3), C=N-NR4(R5); Y2 and Y3 are, independently, O, S, N; A and Z are, independently, C1-6 alkyl; R1 is CF3 or CF2H; R2 and R3 are, independently, C1-8 alkyl, wherein R2 and R3 are optionally joined to form a 5-8 membered ring; R4 and R5 are, independently, C1-8 alkyl; B is a single bond or a double bond; R6 and R7 are, independently, hydrogen or C1-6 alkyl.
PROCESS FOR THE PREPARATION OF AMIDES
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Page/Page column 28, (2009/12/23)
The invention relates to a process for the preparation of fungicidally active compounds such as tricyclic amine derivatives(I). The process involves coupling of a carboxylic 5 acid e.g. a compound of formula (II) with an aniline, e.g. a compound of formula(III) in the presence of a boronic acid catalystor an antimony catalyst (II)(III)(I) wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Het are defined in the specification.
PROCESS FOR THE PRODUCTION OF AMIDES
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, (2008/06/13)
The present invention relates to a process for the preparation of compounds of formula (I) wherein R1 and R2 are each independently of the other hydrogen or C1-C5alkyl and R3 is CF3or CF2H, by a) reaction of a compound of formula (Il) wherein R1 and R2 are as defined for formula (I), with at least one reducing agent to form a compound of formula (III) wherein R1 and R2 are as defined for formula (I), and b) reaction of that compound with at least one reducing agent to form a compound of formula (IV) wherein R1 and R2 are as defined for formula (I), and (c) reaction of that compound with a compound of formula (V) wherein Q is chlorine, fluorine, bromine, iodine, hydroxy or C1-C6alkoxy and R3 is as defined for formula (I), to form the compound of formula (I); and to novel intermediates for use in that process.
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