88186-69-0

Upstream product

• 67-56-1 methanol 
• 88186-87-2 2,3-cis-2-acetoxy-3-bromoflavan 
• 95731-48-9 3-Bromo-2-[(2R,4R)-2-(4-methoxy-phenyl)-chroman-4-yloxy]-2-phenyl-chroman 
• 494-13-3 2-phenyl-4H-chromene 
• 88187-08-0 2-acetoxy-3-bromoflavan-4-one 
• 525-82-6 FLAVONE 
• 31702-30-4 cis-3-bromoflavan 
• 88187-02-4 3-bromo-2-methoxyflavan-4-one 
• 88186-90-7 2,3-cis-3-bromo-2-propionyloxyflavan 

Downstream Products

• 88186-81-6 2,3-cis-3-bromo-2-ethoxyflavan 
• 31702-30-4 cis-3-bromoflavan 
• 88214-92-0 2-methoxyflavan 
• 88186-87-2 2,3-cis-2-acetoxy-3-bromoflavan 
• 88186-72-5 2-methoxy-3,4-bis(p-nitrobenzoyloxy)flavan 
• 88186-89-4 2,3-cis-3-bromo-2-p-tolyloxyflavan 
• 88186-90-7 2,3-cis-3-bromo-2-propionyloxyflavan 
• 88186-97-4 2-acetoxy-3,3-dibromoflavan 
• 88186-71-4 2,3-cis-3,4-cis-2-methoxyflavan-3,4-diol 
• 88186-79-2 3,3-dibromo-2-methoxyflavan 
• 88214-93-1 2-ethoxyflavan 
• 88187-00-2 3,3-dibromoflavan 
• 88186-75-8 3-bromoflav-2-ene 
• 494-12-2 flavan 

Relevant academic research and scientific papers

Synthesis of Biflavonoids in which the Flavan Units are linked through Oxygen from C-2 to C-3 or C-4

Flav-2-enes have been utilised via 2,3-cis-2-acetoxy-3-bromoflavans for the synthesis of C-2-O-C-3- and C-2-O-C-4-linked biflavonoids.For example, 2,3-cis-2-acetoxy-3-bromoflavans react with (+/-)-tetra-O-methylcatechin (18) to give

Reactions of Flav-2-enes and Flav-2-en-4-ones (Flavones)

Flav-2-enes, flavones, and 3-alkyl ethers of flavonols add alcohols and carboxylic acids in the presence of N-bromosuccinimide to give 2-alkoxy- and 2-acyloxy-3-bromoflavans which provide routes to cis-3-bromoflavans by reduction and to 3,4-diols by elimination and reaction with osmium tetraoxide.The 2-acyloxyflavans react with alcohols yielding 2-alkoxyflavans.Flavonols react with N-bromosuccinimide and alcohols to give bromine-free hemiacetals, the known 2,3-dialkoxy-3-hydroxyflavanones.