881883-91-6Relevant articles and documents
Synthesis of Two Stable Nitrogen Analogues of S-Adenosyl-L-methionine
Thompson, Mark J.,Mekhalfia, Abdelaziz,Hornby, David P.,Blackburn, G. Michael
, p. 7467 - 7473 (1999)
Homochiral syntheses of two stable nitrogen analogues of S-adenosyl-L-methionine (AdoMet) are described. In the first analogue, AzaAdoMet, the sulfonium center of AdoMet, is replaced by an N-methyl moiety whose pKa is 7.08. This provides a char