881902-52-9

Upstream product

• 881902-38-1 [2-(3-tert-butoxycarbonylamino-4-cyclopropyl-2-hydroxy-butyrylamino)-acetylamino]-phenyl-acetic acid tert-butyl ester 
• 905927-58-4 (S)-[2-((S)-3-Amino-4-cyclopropyl-2-hydroxy-butyrylamino)-acetylamino]-phenyl-acetic acid tert-butyl ester 
• 881902-59-6 (S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionic acid 
• 905929-73-9 (S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionic acid methyl ester 
• 881902-37-0 (2-acetoxy-3-tert-butoxycarbonylamino-4-cyclopropyl-butyrylamino)-acetic acid methyl ester 
• 905927-56-2 (3-tert-butoxycarbonylamino-4-cyclopropyl-2-hydroxy-butyrylamino)-acetic acid 
• 882004-10-6 (S)-tert-butyl 3-cyclopropyl-1-(methoxy(methyl)amino)-1-oxopropan-2-ylcarbamate 
• 156047-46-0 (2S)-2-[[(tert-butoxy)carbonyl](methyl)amino]-3-cyclopropylpropanoic acid 
• 220416-58-0 2-(tert-butoxycarbonyl-methyl-amino)-3-cyclopropyl-propionic acid methyl ester 
• 881902-36-9 (2-cyclopropyl-1-formyl-ethyl)-carbamic acid tert-butyl ester 
• 394731-25-0 (S)-cyclohexyl-isobutoxycarbonylamino-acetic acid 
• 905929-87-5 (S)-[2-(3-{(S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionylamino}-4-cyclopropyl-2-oxo-butyrylamino)-acetylamino]-phenyl-acetic acid tert-butyl ester 
• 89483-06-7 (2S)-2-[[(tert-butoxy)carbonyl]amino]-3-cyclopropylpropanoic acid 
• 53934-78-4 (S)-2-amino-2-phenylacetic acid tert-butyl ester 

Relevant academic research and scientific papers

Depeptidization efforts on P3-P′2 α-ketoamide inhibitors of HCV NS3-4A serine protease: Effect on HCV replicon activity

Depeptidization efforts of the P3-P2 region of P 3 capped α-ketoamide inhibitor of HCV NS3 serine protease 1 are reported. We clearly established that N-methylation of the P2 nitrogen and modification of the P2′