905929-73-9

Upstream product

• 89483-06-7 (2S)-2-[[(tert-butoxy)carbonyl]amino]-3-cyclopropylpropanoic acid 
• 394731-25-0 (S)-cyclohexyl-isobutoxycarbonylamino-acetic acid 
• 156047-46-0 (2S)-2-[[(tert-butoxy)carbonyl](methyl)amino]-3-cyclopropylpropanoic acid 
• 220416-58-0 2-(tert-butoxycarbonyl-methyl-amino)-3-cyclopropyl-propionic acid methyl ester 

Downstream Products

• 905929-83-1 (S)-[2-((S)-3-{(S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionylamino}-4-cyclopropyl-2-hydroxy-butyrylamino)-acetylamino]-phenyl-acetic acid tert-butyl ester 
• 905929-87-5 (S)-[2-(3-{(S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionylamino}-4-cyclopropyl-2-oxo-butyrylamino)-acetylamino]-phenyl-acetic acid tert-butyl ester 
• 881902-52-9 (S)-[2-(3-{(S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionylamino}-4-cyclopropyl-2-oxo-butyrylamino)-acetylamino]-phenyl-acetic acid 
• 881902-59-6 (S)-2-[((S)-2-Cyclohexyl-2-isobutoxycarbonylamino-acetyl)-methyl-amino]-3-cyclopropyl-propionic acid 

Relevant academic research and scientific papers

Depeptidization efforts on P3-P′2 α-ketoamide inhibitors of HCV NS3-4A serine protease: Effect on HCV replicon activity

Depeptidization efforts of the P3-P2 region of P 3 capped α-ketoamide inhibitor of HCV NS3 serine protease 1 are reported. We clearly established that N-methylation of the P2 nitrogen and modification of the P2′