88234-09-7

Basic information

• Product Name: Phenol, 2-methoxy-6-(2-phenylethenyl)-
• CAS NO: 88234-09-7
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Mol File: 88234-09-7.mol

Chemical Properties

• CAS DataBase Reference: Phenol, 2-methoxy-6-(2-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-methoxy-6-(2-phenylethenyl)-(88234-09-7)
• EPA Substance Registry System: Phenol, 2-methoxy-6-(2-phenylethenyl)-(88234-09-7)

Safety Data

• Hazardous Substances Data: 88234-09-7(Hazardous Substances Data)

Upstream product

• 1100-88-5 benzyltriphenylphosphonium chloride 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 54208-18-3 α-phenyl-2'-acetoxy-3'-methoxycinnamic acid 
• 13466-40-5 (2E, 4E)-5-phenylpenta-2,4-dienal 
• 220063-63-8 2-(1-Hydroxy-2-phenyl-ethyl)-6-methoxy-phenol 
• 591-50-4 iodobenzene 
• 141-82-2 malonic acid 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 951163-69-2 α-phenyl-2-benzoyl-3-methoxycinnamic acid 
• 13246-50-9 benzylchlorotriphenylphosphorane 
• 103-82-2 phenylacetic acid 

Downstream Products

• 14385-51-4 7-methoxy-2-phenylbenzo[b]furan 
• 89122-84-9 2-(4-Bromo-butoxy)-1-methoxy-3-((E)-styryl)-benzene 
• 127003-38-7 2-(4-dimethylaminobutoxy)-3-methoxybibenzyl 
• 195300-59-5 2-methoxy-6-(2-phenylethyl)phenol 

Relevant articles and documents

Preparation method of benzofuran derivative

The invention belongs to the field of organic chemical synthesis, and particularly relates to a preparation method of a benzofuran derivative. According to the specific technical scheme, the preparation method of the benzofuran derivative comprises the fo

Efficient synthesis of functionalized olefins by Wittig reaction using Amberlite resin as a mild base

A convenient procedure for the synthesis of olefins by the reaction of stabilized, semistabilized, and nonstabilized phosphorous ylides with various aldehydes or ketone using Amberlite resin as a mild base is described. Our developed method offers facile and racemization-free synthesis of α,β-unsaturated amino esters and chiral allylic amine. The developed methodology offers mild reaction conditions, high efficiency, and facile isolation of the final products, a practical alternative to known procedures.

One-Step Synthesis of Substituted Benzofurans from ortho- Alkenylphenols via Palladium-Catalyzed C=H Functionalization

A dehydrogenative oxygenation of C(sp2)=H bonds with intramolecular phenolic hydroxy groups has been developed, which provides a straightforward and concise access to structurally diversely benzofurans from ortho-alkenylphenols. The reaction is catalyzed by palladium on carbon (Pd/C) without any oxidants and sacrificing hydrogen acceptors.

A practicable environmentally benign one-pot synthesis of 2-arylbenzofurans at room temperature

An environmentallyfriendly one-pot synthesis of 2-arylbenzofurans under ambient temperature has been developed. It features an ortho-hydroxyl group assisted Wittig reaction of substituted salicylaldehyde followed by an in situ oxidative cyclization. Its advantages include readily available and non-hazardous materials, benign reaction conditions (room temperature, green solvent and one-pot manner), easy work-up and high overall yields. Utilizing this methodology, various 2-aryl-benzofurans including four natural products have been synthesized. The Royal Society of Chemistry 2012.

Direct olefination of benzaldehydes into hydroxy functionalized oligo (p-phenylenevinylene)s via Pd-catalyzed heterodomino Knoevenagel- decarboxylation-Heck sequence and its application for fluoride sensing π-conjugated units

A new approach for one step olefination of benzaldehydes into hydroxy functionalized OPVs is achieved through the first domino Knoevenagel- decarboxylation-Heck sequence using a single catalyst system. The methodology also led to new oxygen based OPV scaffolds capable of selective and visible fluoride recognition in organic or aqueous medium.

Remarkable synergism in methylimidazole-promoted decarboxylation of substituted cinnamic acid derivatives in basic water medium under microwave irradiation: a clean synthesis of hydroxylated (E)-stilbenes

A metal-free protocol for decarboxylation of substituted α-phenylcinnamic acid derivatives in aqueous media is developed, wherein a remarkable synergism between methylimidazole and aq NaHCO3 in polyethylene glycol under microwave furnished the corresponding para/ortho hydroxylated (E)-stilbenes in a mild and efficient manner. The critical role of water in facilitating the decarboxylation imparts an interesting facet to the synthetic utility of water mediated organic transformations. The developed protocol provides a clean alternative to the hitherto indispensable multistep approaches involving toxic quinoline and a copper salt combination as the common decarboxylating agent.

A facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings

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An unusual, mild and convenient one-pot two-step access to (E)-stilbenes from hydroxy-substituted benzaldehydes and phenylacetic acids under microwave activation: a new facet of the classical Perkin reaction

A mild and convenient one-pot two-step synthesis of hydroxystilbenes with trans selectivity has been developed through a modified Perkin reaction between benzaldehydes and phenylacetic acids bearing 4- or 2-hydroxy substitution at the aromatic ring, in the presence of piperidine-methylimidazole and polyethylene glycol under microwave irradiation. The observation of a simultaneous condensation-decarboxylation leading to the unusual formation of hydroxystilbenes in lieu of α-phenylcinnamic acid reveals an interesting facet to the classical Perkin reaction. The developed protocol provides a green alternative to the prevalent methods employing a toxic decarboxylating agent in the form of quinoline/Cu salt, and the requirement for harsh protection-deprotection steps for the synthesis of hydroxylated stilbenes.

A MICROWAVE INDUCED ONE POT PROCESS FOR THE PREPARATION OF ARYLETHENES

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Iron in the service of chromium: The ortho-benzannulation of trans,trans-dienyl Fischer carbene complexes

Chromium Fischer carbene complexes with trans,trans-dienyl substituents on the carbene carbon will react with diiron nonacarbonyl to give 2-alkoxycyclohexa-2,4-dienone iron tricarbonyl complexes and/or 2-alkoxyphenols in excellent yields. In the presence