88264-13-5Relevant academic research and scientific papers
Regioselective functionalization of the thiazole scaffold using TMPMgCl?LiCl and TMP2Zn?2MgCl2?2LiCl
Dunst, Cora,Knochel, Paul
, p. 6972 - 6978 (2011/10/04)
A general method for the synthesis of 2,4,5-trisubstituted thiazoles has been developed. Starting from commercially available 2-bromothiazole, successive metalations using TMPMgCl?LiCl or TMP2Zn?2MgCl 2?2LiCl lead to the correspondin
Antiinflammatory agents, XVII: 4,5-Bis-(4-methoxyphenyl)-2-(arylthio)azoles with antiinflammatory activity
Klose,Niedballa,Schwarz,Bottcher
, p. 941 - 951 (2007/10/02)
The syntheses of 4,5-bis(4-methoxyphenyl)-2-(arylthio)imidazoles, -thiazoles and -oxazoles are described and their inflammatory activities are compared. Thioethers, sulfoxides, and sulfones of the phenyl, 4-fluorophenyl, and 2-thienyl derivatives were inv
