882687-80-1 Usage
General Description
4-Iodo-2,2-dimethyl-tetrahydro-pyran, also known as IDTP, is a chemical compound with the molecular formula C7H13IO. It is a clear, colorless liquid that is primarily used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. IDTP has a tetrahydropyran ring structure and is substituted with a methyl group at the 2 and 2 positions and an iodine atom at the 4 position. It is commonly used as a reagent in organic synthesis and is known for its ability to undergo various reactions, including halogenation, and can be used to introduce iodine into organic molecules. It is important to handle IDTP with care as it is considered a hazardous chemical and is harmful if swallowed or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 882687-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,2,6,8 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 882687-80:
(8*8)+(7*8)+(6*2)+(5*6)+(4*8)+(3*7)+(2*8)+(1*0)=231
231 % 10 = 1
So 882687-80-1 is a valid CAS Registry Number.
882687-80-1Relevant articles and documents
Iodine-promoted Prins-cyclization of ketones - A facile synthesis of spirocyclic-4-iodotetrahydropyrans and 5,6-dihydro-2H-pyrans
Yadav,Reddy, B. V. Subba,Krishna, V. Hari,Swamy,Kumar, G. G. K. S. Narayana
, p. 412 - 415 (2007)
Homoallylic and homopropargylic alcohols undergo smooth coupling with ketones in the presence of molecular iodine at ambient temperature to produce spirocyclic-4-iodotetrahydropyrans and 5,6-dihydro-2H-pyrans, respectively, in high yields in a short reaction time with high selectivity. The use of molecular iodine makes this procedure quite simple, more convenient, and cost-effective.
TMSI mediated Prins-type cyclization of ketones with homoallylic and homopropargylic alcohol: Synthesis of 2,2-disubstituted-, spirocyclic-4-iodo- tetrahydropyrans and 5,6-dihydro-2H-pyrans
Sabitha, Gowravaram,Reddy, K. Bhaskar,Bhikshapathi,Yadav
, p. 2807 - 2810 (2006)
The Prins-type cyclization of ketones with homoallylic and homopropargylic alcohols in the presence of TMSI generated in situ from TMSCl and NaI produced 2,2-disubstituted- or spirocyclic-4-iodo-tetrahydropyrans and spirocyclic-4-iodo-5,6-dihydro-2H-pyran
