88271-29-8 Usage
Uses
Used in Pharmaceutical Industry:
Pioglitazone is used as an anti-diabetic medication for managing type 2 diabetes. It is prescribed to improve insulin sensitivity and lower blood glucose levels in patients with this condition.
Used in Combination Therapy:
Pioglitazone is often used in combination with other anti-diabetic medications to effectively manage blood sugar levels in individuals with type 2 diabetes. This combined approach helps to achieve better glycemic control and reduce the risk of diabetes-related complications.
Used in Lifestyle Modification Programs:
In addition to its pharmaceutical applications, pioglitazone is also used as part of comprehensive lifestyle modification programs for patients with type 2 diabetes. These programs typically include dietary changes, regular physical activity, and weight management, all of which work synergistically with pioglitazone to improve overall diabetes management.
Check Digit Verification of cas no
The CAS Registry Mumber 88271-29-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,2,7 and 1 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88271-29:
(7*8)+(6*8)+(5*2)+(4*7)+(3*1)+(2*2)+(1*9)=158
158 % 10 = 8
So 88271-29-8 is a valid CAS Registry Number.
88271-29-8Relevant academic research and scientific papers
Proton and Zinc(II) Complexes of 2-(Polyhydroxyalkyl)thiazolidine-4-carboxylic acid Derivatives
Gajda, Tamas,Nagy, Laszlo,Burger, Kalman
, p. 3155 - 3160 (2007/10/02)
The protonation and zinc-ion co-ordination equilibria of 2-(polyhydroxyalkyl)thiazolidine-4-carboxylic acid derivatives have been studied by potentiometric titration in the range pH 1.5-8.In most cases the formation of complexes with a metal-to-ligand ratio of 1:2 was demonstrated, but at above pH 6 mixed-ligand complexes involving hydroxide-ion co-ordination were also observed.The protonation and complex-formation constants were shown to depend on the structure of the polyhydroxy chains.In the case of the protonation constants this is due to the rearrangement of the intramolecular hydrogen-bonding network, while the complex-formation constants depend on the conformation of the OH groups on the first carbon atoms of the polyol chains.
