88288-12-4

Usage

Uses

Used in Pharmaceutical Industry:
N-Acetyl 5-bromo-2-fluoroaniline is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties. Its unique structure allows for the creation of molecules with targeted actions, potentially leading to more effective treatments.
Used in Dye Industry:
In the dye industry, N-Acetyl 5-bromo-2-fluoroaniline is utilized as a key component in the production of dyes. Its chemical structure enables the creation of dyes with specific color characteristics and stability, which are essential for various applications including textiles, plastics, and printing inks.
Used in Agrochemical Industry:
N-Acetyl 5-bromo-2-fluoroaniline is employed as an intermediate in the development of agrochemicals, such as pesticides and herbicides. Its unique properties allow for the synthesis of compounds that can effectively control pests and weeds, contributing to increased crop yields and agricultural productivity.
Used in Organic Synthesis:
N-Acetyl 5-bromo-2-fluoroaniline is used as a versatile building block in organic synthesis for its potential to form a variety of complex organic molecules. Its presence of both bromine and fluorine atoms provides opportunities for further chemical reactions, making it a valuable precursor in the synthesis of specialized organic compounds for research and industrial applications.

InChI:InChI=1/C8H7BrFNO/c1-5(12)11-8-4-6(9)2-3-7(8)10/h2-4H,1H3,(H,11,12)

Upstream product

• 621-38-5 3-bromoacetanilide 
• 2924-09-6 5-bromo-2-fluoroaniline 
• 108-24-7 acetic anhydride 
• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 7439-89-6 iron 

Downstream Products

• 874959-51-0 N-[5-(cis-3,5-dimethyl-1-piperazinyl)-2-fluorophenyl]acetamide 

Relevant academic research and scientific papers

NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES

Provided are near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.

NOVEL COMPOUNDS FOR THE TREATMENT OF CYSTIC FIBROSIS

The present invention is directed to novel compounds, pharmaceutical compositions comprising such compounds, and the methods of making and using the same. These compounds are useful as modulators of Cystic Fibrosis Transmembrane Conductor Regulator (CFTR). The present invention also relates to methods of treating or lessening the severity of cystic fibrosis in a patient. These compounds may be used alone or in combination with one or more secondary active agents.

PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS

The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Re, Rf and Y are as defined in the specification. The compounds are partial or full agonists at the growth hormone secretagogue (GHS) receptors . Pharmaceutical compositions comprising the compounds, methods of preparing the compounds, uses of the compounds and methods involving the compounds are also provided.

1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof

To provide a composition having a steroid C17,20-lyase inhibitory activity and useful as an agent for the prophylaxis or treatment of prostatism and tumors such as breast cancer. A compound represented by the formula: wherein R is a hydrogen atom or a protecting group, R1is a lower alkyl group or a cyclic hydrocarbon group, R2is an aromatic hydrocarbon group optionally having substituents or an aromatic heterocyclic group optionally having substituents, R3is a hydrocarbon group optionally having substituents, a hydroxyl group optionally having substituents, a thiol group optionally having substituents, an amino group optionally having substituents, an acyl group or a halogen atom, and n is an integer of 0 to 4, and a salt thereof have a steroid C17,20-lyase inhibitory activity, and are useful as an agent for the pophylaxis or treatment of prostatism and tumors such as beast cancer and the like.

A Novel Electrophilic Fluorination of Activated Aromatic Rings Using Acetyl Hypofluorite, Suitable also for Introducing (18)F into Benzene Nuclei

Acetyl hypofluorite (1) is a new compound that serves as a novel electrophilic fluorinating agent.It is special in the sense that, while it is very reactive, it is still a milder reagent than other fluoroxy compounds such as CF3OF or CF3COOF.It is synthesized directly from elemental fluorine and is used without any isolation or purification.The hypofluorite 1 reacts efficiently and selectively with activated aromatic rings,particularly phenol and aniline derivatives after suitable protection of the hydroxyl and the amino groups.The net result of the reaction is partly according to classical aromatic electrophilic substitution.Unlike such a substitution, however, the electrophilic fluorine atom of 1 substitutes mainly an ortho hydrogen and only occasionally small amounts of p-fluoro derivatives are found.Evidence supports the mechanism for this aromatic fluorination as being mainly an addition-elimination one.In many cases the electrophilic aromatic fluorinations can replace the classical 60-year-old Balz-Schiemann method, which until today is probably the most used procedure.Since aromatic fluorination with 1 is a very fast reaction and since 1 is produced directly from elemental fluorine, this is probably one of the best ways for introduction of the short-living radioisotope (18)F into activated aromatic rings.This will greatly encourage the synthesis of compounds suitable for use in the rapidly developing field of positron emitting transaxial tomography, which in itself depends on the efficient and easy supply of compounds possessing positron emitting isotopes.