882990-56-9

Upstream product

• 51-35-4 4R-4-hydroxyproline 
• 114676-48-1 (2S,4R)-1-benzyl-4-hydroxyproline methyl ester 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 882990-52-5 (2S,4R)-1-benzyl-4-[(tert-butyldiphenylsilyl)oxy]-2-methoxycarbonylpyrrolidine 

Downstream Products

• 1318129-31-5 (3R,5R)-1-benzyl-5-(tert-butyldiphenylsilyloxy)piperidin-3-amine 
• 1318128-43-6 (2S,4R)-2-(azidomethyl)-1-benzyl-4-(tert-butyldiphenylsilyloxy)pyrrolidine 
• 1318128-40-3 (3R,5R)-3-azido-1-benzyl-5-(tert-butyldiphenylsilyloxy)piperidine 
• 1374647-31-0 N-{[(2S,4R)-1-benzyl-4-(tert-butyldiphenylsilyloxy)pyrrolidin-2-yl]methyl}-4-methyl-N-tosylbenzenesulfonamide 
• 1374647-33-2 N-[(3R,5R)-1-benzyl-5-(tert-butyldiphenylsilyloxy)piperidin-3-yl]-4-methyl-N-tosylbenzenesulfonamide 

Relevant academic research and scientific papers

Enantioselective diethylzinc addition to aromatic and aliphatic aldehydes using (3R,5R)-dihydroxypiperidine derivatives catalyst

A series of chiral (3R,5R)-dihydroxypiperidine derivatives 3a-f were conveniently prepared from trans-4-hydroxy-l-proline and applied to the catalytic enantioselective addition of diethylzinc to benzaldehyde and heptanal. Among them, 3d was found to show