88303-27-9Relevant academic research and scientific papers
Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst
Gangloff, Anthony R.,Litvak, Joane,Shelton, Emma J.,Sperandio, David,Wang, Vivian R.,Rice, Kenneth D.
, p. 1441 - 1443 (2007/10/03)
Tetrabutylammonium fluoride (TBAF) was found to be a mild and efficient catalyst for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles. Using 0.1 - 1.0 equivalents of TBAF in THF for 1 - 24 h at room temperature, alkanoyl- and aroyloxyamidines were converted in high yield to the corresponding 3,5-disubstituted-1,2,4-oxadiazoles. A variety of R and R′ substituents were investigated.
SYNTHESIS, SPECTROSCOPIC STUDIES AND MOLECULAR ORBITAL CALCULATIONS OF O-ACYLBENZAMIDOXIMES
Srivastava, Rajendra M.,Ramos, Mozart N.,Mendes e Silva, Leda M.
, p. 845 - 850 (2007/10/02)
O-Acyl derivatives of benzamidoxime, 1a, and tolylamidoximes, 1b-g, have been prepared.Out of seven compounds, four (viz., 1b,c,e,f) are new.The structure of these compounds were determined with the aid of UV, IR and NMR spectra.Molecular orbital calculations have been performed using the CNDO/2 method in order to obtain more insight into the configuration and conformation of these molecules.Our results support the view that Z configuration at the C=N bond and the ap conformation at the N-O bond in the O-acyl derivatives are the most stable ones.
