88344-63-2Relevant academic research and scientific papers
FeCl3-promoted formation of C-C bonds: Synthesis of substituted quinolines from imines and electron-deficient alkynes
Li, Yu-Feng,Wu, Zheng-Guang,Shi, Jie,Pan, Yi,Bu, Hong-Zhong,Ma, Hong-Fei,Gu, Jia-Chao,Huang, Hao,Wang, Yao-Zhu,Wu, Lin
, p. 8971 - 8975 (2015/03/04)
An efficient method for the synthesis of substituted quinolines is described. By FeCl3-promoted C-C bond formation, 2,3-disubstituted and 2,3,4-trisubstituted quinolines were successfully synthesized from the reaction between imines and electron-deficient alkynes in good yields. The reaction can also be performed in a sequential three-component manner by using aromatic amines and aromatic aldehydes instead of the corresponding imines.
THE REACTION OF IMIDOYL RADICALS WITH MULTIPLE CARBON-CARBON BONDS
Leardini, Rino,Nanni, Daniele,Tundo, Antonio,Zanardi, Giuseppe
, p. 637 - 642 (2007/10/02)
A general view on the reaction between imidoyl radicals and carbon-carbon double or triple bonds is given; the synthesis of substituted quinolines starting from imines and alkenes is described, pointing out the differences with respect to the analogous reaction performed with alkynes.
Photochemistry of Dimethyl Quinoline-3,4-dicarboxylate N-Oxides
Irvine, Robert W.,Summers, John C.,Taylor, Walter C.
, p. 1419 - 1430 (2007/10/02)
The photochemical rearrangement of 2-methyl and 2-aryl substituted dimethyl quinoline-3,4-dicarboxylate N-oxides has been studied.In methanol or methanol/chloroform solutions the major product was the 1-methyl- or 1-aryl-quinolin-2-(1H)-one in which the substituent at C2 has migrated to nitrogen.The yield of these products was increased in a dark reaction subsequent to the irradiation.In acetonitrile solutions the initial major product was the corresponding 3,1-benzoxazepine; subsequent reactions yielded inter alia indole derivatives.
