88369-18-0

Upstream product

• 5606-55-3 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid ethyl ester 

Downstream Products

• 88369-19-1 7-chloro-5-phenyl-3-hydroxymethyl-3-deuterio-1,3-dihydro-2H-1,4-benzodiazepin-2-one 
• 88369-21-5 C₂₃H₁₈⁽²⁾HClN₂O₄S 
• 88369-22-6 7-chloro-5-phenyl-3-methyl-2,2,3,3'-tetradeuterio-1,3-dihydro-2H-1,4-benzodiazepine 
• 88369-23-7 7-chloro-5-phenyl-3-methyl-3-deuterio-1,3-dihydro-2H-1,4-benzodiazepine 

Relevant academic research and scientific papers

Chiral 1,4-benzodiazepines. XII (1). Conformation in a solution of 7-chloro-5-phenyl-3(S)methyl-1,3-dihydro-2H-1,4-benzodiazepine

Deuterium labeled congeners of 7-chloro-5-phenyl-3(S)-methyl-1,3-dihydro-2H-1,4-benzodiazepine (8), i.e. compounds 9 and 16-18 were prepared and their lis-nmr spectra run. For computational studies compounds 9 and 16 were chosen. The results of lis measur

Chiral 1,4-Benzodiazepin-2-one, Template for Enantioselective Synthesis of α-Amino Acids and their α-Deuterio Congeners

Absolute conformation of 7-chloro-5-phenyl-1--1,3-dihydro-2H-1,4-benzodiazepin-2-one (1c) in crystal, and its inversion rate in solution were determined, enabling prognosis of direction of asymmetric induction during C(3)-alkylation.